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首页> 外文期刊>Mayo Clinic Proceedings: Innovations, Quality & Outcomes >Clinical Characteristics and Risk Factors for Death of Hospitalized Patients With COVID-19 in a Community Hospital: A Retrospective Cohort Study
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Clinical Characteristics and Risk Factors for Death of Hospitalized Patients With COVID-19 in a Community Hospital: A Retrospective Cohort Study

机译：社区医院Covid-19住院治疗患者死亡的临床特征及危险因素：回顾性队列研究

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Objective To describe the clinical characteristics, outcomes, and risk factors for death of patients with coronavirus disease 2019 (COVID-19) in a community hospital setting. Patients and Methods This single-center retrospective cohort study included 313 adult patients with laboratory-confirmed COVID-19 admitted to a community hospital in Cook County, Illinois, from March 1, 2020, to May 25, 2020. Demographics, medical history, underlying comorbidities, symptoms, signs, laboratory findings, imaging studies, management, and progression to discharge or death data were collected and analyzed. Results Of 313 patients, the median age was 68 years (interquartile range, 59.0-78.5 years; range, 19-98 years), 182 (58.1%) were male, 119 (38%) were white, and 194 (62%) were admitted from a long-term care facility (LTCF). As of May 25, 2020, there were 212 (67.7%) survivors identified, whereas 101 (32.3%) nonsurvivors were identified. Multivariable Cox regression analysis showed increasing hazards of inpatient death associated with older age (hazard ratio [HR] 1.02; 95% CI, 1.01-1.04), LTCF residence (HR, 3.23; 95% CI, 1.68-6.20), and quick Sequential Organ Failure Assessment scores (HR, 2.59; 95% CI, 1.78-3.76). Conclusion In this single-center retrospective cohort study of 313 adult patients hospitalized with COVID-19 illness in a community hospital in Cook County, Illinois, older patients, LTCF residents, and patients with high quick Sequential Organ Failure Assessment scores were found to have worse clinical outcomes and increased risk of death.
机译：目的介绍2019年冠状病毒疾病患者死亡（Covid-19）在社区医院环境中死亡的临床特征，结果和危险因素。患者和方法这种单中心回顾队列研究包括313名成年患者，实验室确认的Covid-19涉及到伊利诺伊州库克县的社区医院，于2020年5月25日，2020年5月25日。人口统计学，病史，潜在的收集并分析了分析症状，症状，征兆，实验室发现，成像研究，管理和进展的进展。结果313名患者，中位年龄为68岁（四分位数，59.0-78.5岁;范围，19-98岁），182名（58.1％）是男性，119（38％）是白色，194（62％）从长期护理机构（LTCF）中录取。截至2020年5月25日，鉴定了212例（67.7％）幸存者，而鉴定了101例（32.3％）非尿毒剂。多变量的Cox回归分析表明，与年龄较大（危险比[HR] 1.02; 95％CI，1.01-1.04），LTCF住宅（HR，3.23; 95％CI，1.68-6.20）和快速顺序相关的感染性死亡危害器官衰竭评估分数（HR，2.59; 95％CI，1.78-3.76）。结论在这种单中心回顾性队列队列的313名成人患者与Covid-19疾病住院治疗康西郡，伊利诺伊州，老年患者，LTCF居民，以及高次顺序器官失效评估分数的患者有更糟临床结果和增加的死亡风险。

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