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首页> 外文期刊>Scandinavian journal of Work, Environment and Health >Efficacy of intermittent exposure to bright light for treating maladaptation to night work on a counterclockwise shift work rotation
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Efficacy of intermittent exposure to bright light for treating maladaptation to night work on a counterclockwise shift work rotation

机译：间歇暴露于明亮光的疗效在逆时针换档工作旋转中处理夜间工作的亮光

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Rotating shift work is associated with adverse outcomes due to circadian misalignment, sleep curtailment, work-family conflicts, and other factors. We tested a bright light countermeasure to enhance circadian adaptation on a counterclockwise rotation schedule. Methods Twenty-nine adults (aged 20–40 years; 15 women) participated in a 4-week laboratory simulation with weekly counterclockwise transitions from day, to night, to evening, to day shifts. Each week consisted of five 8-hour workdays including psychomotor vigilance tests, two days off, designated 8-hour sleep episodes every day, and an assessment of circadian melatonin secretion. Participants were randomized to a treatment group (N=14), receiving intermittent bright light during work designed to facilitate circadian adaptation, or a control group (N=15) working in indoor light. Adaptation was measured by how much of the melatonin secretion episode overlapped with scheduled sleep timing. Results On the last night shift, there was a greater overlap between melatonin secretion and scheduled sleep time in the treatment group [mean 4.90, standard deviation (SD) 2.8 hours] compared to the control group (2.62, SD 2.8 hours; P=0.002), with night shift adaptation strongly influenced by baseline melatonin timing (r2=-0.71, P=0.01). While the control group exhibited cognitive deficits on the last night shift, the treatment group’s cognitive deficits on the last night and evening shifts were minimized. Conclusions In this laboratory setting, intermittent bright light during work hours enhanced adaptation to night work and subsequent readaptation to evening and day work. Light regimens scheduled to shift circadian timing should be tested in actual shift workers on counterclockwise schedules as a workplace intervention.
机译：轮班工作与不良结果由于生理失调，睡眠缩减，工作与家庭的冲突，以及其他因素有关。我们测试了明亮的光线对策，加强对逆时针旋转的时间表昼夜适应。方法二十九成年人（年龄20-40岁; 15名）参加了为期4周的实验室模拟与天每周逆时针转场，到晚上，早出晚归，一天班。每个星期，包括了5个8小时工作日，包括精神运动警觉试验，休息两天，每天指定8小时的睡眠发作，和昼夜褪黑激素分泌的评估。参加者随机治疗组（N = 14），设计成有利于昼夜改编或在室内光工作对照组（N = 15）的工作期间接收间歇式的亮的光。适应是多少排定休眠定时重叠的褪黑激素分泌情节的测量。结果在最后夜班，有治疗组褪黑激素分泌和预定睡眠时间之间的较大的重叠[平均4.90，标准偏差（SD）2.8小时]相比于对照组（2.62，SD2.8小时; P = 0.002 ），与由基线褪黑素定时（R2 = -0.71，P = 0.01）的强烈影响夜班适应。而对照组的最后一个夜班展出认知障碍，治疗组的最后一晚，晚转变认知缺陷降低到最低限度。结论：在此实验室环境中，在工作时间内间歇强光增强适应夜班工作，并随后重新适应于晚上和白天的工作。预定转移昼夜定时光方案应在实际轮班工人在逆时针时间表作为工作场所干预进行测试。

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