首页> 外文期刊>Substance Abuse Treatment, Prevention, and Policy >Acute Toxic Effects of the New Psychoactive Substance “Voodoo” among Patients presented to the Poison Control Center of Ain Shams University Hospitals (PCC-ASUH), Egypt, during 2017
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Acute Toxic Effects of the New Psychoactive Substance “Voodoo” among Patients presented to the Poison Control Center of Ain Shams University Hospitals (PCC-ASUH), Egypt, during 2017

机译:新的精神活性物质“伏都教”患者患者毒药院毒理毒理(PCC-ASUH),埃及,2017年

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Voodoo is a heterogeneous mixture of psychoactive substances that has recently grown in popularity among youth in Egypt. Patients can present with a variety of manifestations that may lead to death in some cases. This study assessed the acute toxic effects of voodoo among patients presented to the Poison Control Center of Ain Shams University Hospitals (PCC-ASUH) during a one year period. This is a retrospective study of all patients presented with voodoo intoxication at the PCC-ASUH from 1?January 2017 to 31 December 2017. Clinical data, routine laboratory findings, and ECG results as well as duration of hospitalization and outcome were compiled from hospital records. Seventy-one voodoo intoxication cases meeting the inclusion criteria were analyzed (mean age: 25.19?±?9.54 years, range: 15–50 years, 97.2?% male). Pulse, blood pressure, and respiratory rate were normal in more than half of all patients. Neurological abnormalities including agitation, hallucinations, disturbance of consciousness were the most frequent manifestations. Respiratory acidosis was the most common laboratory finding (54.9?%), followed by increased serum urea (43.6?%), hypokalemia (33.8?%), hyperglycemia (28.1?%), and leukocytosis (26.7?%). The most common ECG finding was sinus tachycardia (31?%), followed by QT prolongation (15.4?%). More than half of the studied patients (53.5?%) co-administered other illicit substances, most frequently cannabis and tramadol. Most patients recovered fully and were discharged, but death occurred in two cases. Voodoo toxicity can manifest with many presentations, hampering timely diagnosis. Clinicians should consider possible voodoo poisoning in patients presenting with a history of drug use with neurological symptoms, and they should conduct follow-up arterial blood gases, electrolytes and ECG as voodoo may contain potentially fatal psychoactive substances.
机译:伏都教是最近在埃及青年中普及的精神活性物质的异质混合物。患者可以在某些情况下出现各种可能导致死亡的表现形式。本研究评估了患有一年内An Shams大学医院(PCC-ASUH)毒药控制中心的患者伏都豆的急性毒性作用。这是从1月1日到2017年1月到2017年1月31日的PCC-ASUH展示的所有患者的回顾性研究。临床资料,常规实验室调查结果和ECG结果以及住院和结果的持续时间是从医院记录编制的。分析了七十一只伏都毒毒瘾的案件(平均年龄:25.19?±9.54年,范围:15-50岁,男性97.2?%男性)。脉冲,血压和呼吸率在所有患者的一半以上都是正常的。神经学异常,包括搅拌,幻觉,意识紊乱是最常见的表现形式。呼吸酸中毒是最常见的实验室发现(54.9?%),其次是血清尿素(43.6μm),低血糖(28.1〜Δ%)和白细胞增多(26.7μl)(26.7μl%)。最常见的ECG发现是鼻窦(31?%),其次是QT延长(15.4?%)。超过一半的研究患者(53.5?%)共同施用其他非法物质,最常大麻和曲马多。大多数患者完全恢复并出院,但死亡发生在两种情况下。 Voodoo毒性可以表现出许多演示,妨碍及时诊断。临床医生应考虑患有患者患有药物用史的患者可能的毒品毒性,并且它们应该进行随访动脉血液,电解质和ECG,因为伏都杜栎可能含有可能致命的精神活性物质。

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