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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Biosynthesis and Characterisation of Ellagic Acid Coupled Silver Nanoparticles- An In-vitro Study
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Biosynthesis and Characterisation of Ellagic Acid Coupled Silver Nanoparticles- An In-vitro Study

机译：鞣酸偶联银纳米粒子的生物合成与表征 - 体外研究

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Nanomedicine dominated the world of therapeutics and diagnostics. Horizons are extending daily to identify a piece of the puzzle that helps us produce eco-friendly and cost-effective nanoparticles. In this, authors tried to synthesise a novel Silver Nanoparticle Coated with Ellagic Acid (EA-AgNPs) obtained from pomegranate using a simple method and explore its characterisation precisely.Aim: To biosynthesise and assess the characterisation of Ellagic Acid coupled Silver Nanoparticles.Materials and Methods: The study assessed the portrayal of EA-AgNPs were evaluated using various analytical techniques. Firstly, to analyse: the size of the EA-AgNPs using Ultraviolet (UV)-Visible Spectrometer; Secondly to determine the hydrodynamic size and its dispersity using Dynamic Light Scattering (DLS) and Zeta potential; thirdly to quantify the average size of EA-AgNPs by using Scanning Electron microscope (SEM); and lastly to identify the functional groups by using Fourier Transform Infrared Spectroscopy (FTIR) method. Descriptive statistics were used to analyse the results.Results: Brownish colour change and shift of peak wavelength from 430 to 423 nm using UV-Visible Spectrometer analysis confirmed the formation and stability of EA-AgNPs. The DLS analysis revealed that EA-AgNPs were in nanosize (129.7 nm) with less aggregated polydispersity index (0.483). The Zeta potential confirmed that this newly synthesised nanoparticle was negatively charged -0.268mv. The SEM determination confirmed the formation of spherical-shaped nanoparticles with sizes ranging from 84.34-98.80 nm. The FTIR revealed EA-AgNPs exhibited different functional groups, which help to prevent particle aggregation.Conclusion: In this work, the novel EA-AgNPs exhibited the apt characterisation needed for an effective and cost-efficient nanoparticle that could be effectively tapped in various fields of nanodentistry.
机译：Nanomedicine主导了治疗方法和诊断的世界。 Horizo​​ ne每天延伸，以识别一块有助于我们生产环保且经济高效的纳米颗粒的拼图。在这方面，作者试图合成涂有由石榴获得的新型银纳米颗粒使用简单的方法，并将其表征精确探讨了，并评估了鞣酸偶联银纳米颗粒的表征。材料和方法：采用各种分析技术评估了评估EA-AGNP的描绘。首先，使用紫外线（UV）可见光光谱仪分析：EA-AGNP的尺寸;其次，使用动态光散射（DLS）和Zeta电位确定流体动力学尺寸及其分散性;第三，通过使用扫描电子显微镜（SEM）量化EA-AGNP的平均尺寸;最后通过使用傅里叶变换红外光谱（FTIR）方法来识别功能组。描述性统计用于分析结果。结果：使用紫外可见光谱仪分析，430至423nm的褐色颜色变化和峰值波长的偏移证实了EA-AGNP的形成和稳定性。 DLS分析显示EA-AgNP纳米氧化纳米（129.7nm），具有较少的聚集的多分散性指数（0.483）。 Zeta电位证实，这种新合成的纳米颗粒带来了带负电荷-0.268mV。 SEM测定证实了球形纳米粒子的形成，尺寸范围为84.34-98.80nm。 FTIR揭示了EA-agnps表现出不同的官能团，有助于防止颗粒聚集。结论：在这项工作中，新的EA-agnps表现出可有效且经济高效的纳米粒子所需的APT表征，这些纳米粒子可以有效地分布在各个领域纳米例。

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