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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Old Wine in a New Bottle: Acromegaly Presenting as Diabetic Ketoacidosi
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Old Wine in a New Bottle: Acromegaly Presenting as Diabetic Ketoacidosi

机译：在一个新的瓶子里的老葡萄酒：临床呈糖尿病ketoacidosis

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摘要

Acromegaly is a rare disease characterised by chronic excess of Growth Hormone (GH) levels. Insulin signalling is impaired, gluconeogenesis is excess and peripheral insulin resistance is increased in acromegaly causing hyperglycaemia and diabetes. Diabetic Ketoacidosis (DKA) is a rare but known complication of diabetes in acromegaly. Most cases of acromegaly come into light due to the classical soft tissue changes in the face and extremities. A high index of suspicion is required to diagnose this condition in early stage. Here, a case of 22-years-old male presented with DKA and on investigation was found to have acromegaly due to a GH secreting pituitary macroadenoma. This management and subsequent follow-up of the case along with review of literature is also done. Such a presentation of acromegaly was rare but rewarding.
机译：棘手症是一种罕见的疾病，其特征在于慢性过量的生长激素（GH）水平。 胰岛素信号传递受损，葡糖生成过量，骨质血糖患者造成高血糖和糖尿病的外周胰岛素抵抗。 糖尿病酮症症（DKA）是古代糖尿病患者罕见但已知的复杂性。 由于面部和四肢的典型软组织变化，大多数棘手症病例变为光线。 在早期阶段诊断这种情况需要高度的怀疑指数。 在此，发现DKA和调查呈现的22岁男性，由于GH分泌垂体脑膜瘤，发现具有棘手症。 此管理和随后的案件后续行动以及文献的审查也是如此。 这种棘手蛋白的呈现是罕见的，但有价值。

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