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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Screening for Carcinoma Cervix by Comparing Pap Smear Cytology, Histopathology with Colposcopy in Unhealthy Cervix
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Screening for Carcinoma Cervix by Comparing Pap Smear Cytology, Histopathology with Colposcopy in Unhealthy Cervix

机译:通过对比较宫颈癌,组织病理学与阴道镜下的癌宫颈筛查癌子宫颈筛查

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Cervical cancer is one of the most frequent genital tract cancers and accounts for 80% of all female cancers worldwide. Annually, the incidence is about five lacs and 2,80,000 people die due to carcinoma cervix yearly. In India, 1,26,000 new cases are detected and 71,000 deaths occur annually. Cervical cancer is a preventable condition, since it is associated with prolonged preinvasive stage, so that early screening and appropriate treatment can be undertaken to prevent the progression into invasive stage.Aim: To compare papanicolaou smear cytology, colposcopy and colposcopy guided biopsy (histopathology) in detecting premalignant and malignant lesions of the cervix.Materials and Methods: A cross-sectional study was carried out in Department of Obstetrics and Gynaecology at RL Jalappa Hospital and Research Centre, Kolar, Karnataka, India. The study period was from October 2018 to June 2020 and 90 study subjects were included into the study. All the study subjects enrolled were subjected to Papanicolaou (Pap) smear, colposcopy and colposcopy directed biopsy. The data was statistically analysed for sensitivity, specificity, positive predictive value, negative predictive value and accuracy of pap smear and colposcopy, with considering colposcopy directed biopsy as the gold standard for diagnosis.Results: Maximum number of women was found in the age group of more than 50 years (44.4%), mean age was 52±11 years. Majority of the women were multipara accounting for 95.6%. Pap smear had a sensitivity and specificity of 69.2% and 88.2%, respectively. The colposcopy had sensitivity of 97.4% specificity of 88.5%. The colposcopy had higher sensitivity but similar specificity as Pap smear.Conclusion: Colposcopy has a good association with Pap smear and histopathology in diagnosis of premalignant and malignant lesion in unhealthy cervix. Hence, its satisfactory diagnostic efficacy makes it a realiable for diagnosis of malignant and pre malignant lesion.
机译:宫颈癌是最常见的生殖道癌症之一,占全世界所有女性癌症的80%。每年,该发病率约为5个LAC,2,80,000人因癌子宫颈每年死亡。在印度,检测到126,000例新病例,每年发生71,000人死亡。宫颈癌是可预防的病症,因为它与延长的预衰减阶段相关,因此可以进行早期筛查和适当的治疗,以防止进展进入侵入性阶段。优雅:比较papanicolaou涂片细胞学,阴道镜检查和阴道镜检查引导活组织检查(组织病理学)在检测子宫颈的前一种和恶性病变。和方法:在RL Jalappa医院和研究中心,Kolar,Karnataka,India的妇产科进行横断面研究。研究期为2018年10月至6月20日至6月20日,并将90项研究受试者纳入该研究。纳入的所有研究受试者患有帕帕内尼索洛(PAP)涂片,阴道镜检查和阴道镜检查的活检。统计分析了敏感性,特异性,阳性预测值,对PAP涂片和阴道镜的阳性预测值和准确性的统计分析,考虑到Colposcopoce定向活组织检查作为诊断的金标准。结果:在年龄组中发现了最大妇女人数超过50年(44.4%),平均年龄为52±11年。大多数女性是多原人占95.6%。 PAP涂片的敏感性和特异性分别为69.2%和88.2%。阴道镜检查的敏感性为97.4%的特异性为88.5%。阴道镜检查具有更高的敏感性,但与PAP涂片相似的特异性。结论:Colposcopy与PAP涂片和组织病理学的良好关联,在不健康的子宫颈诊断前嗜血剂和恶性病变的诊断。因此,其令人满意的诊断疗效使其成为诊断恶性和患者的恶性病变的态度。

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