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首页> 外文期刊>Indian Journal of Critical Care Medicine >Utility of Serum Procalcitonin in Diagnosing Paroxysmal Sympathetic Hyperactivity in Patients with Traumatic Brain Injury
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Utility of Serum Procalcitonin in Diagnosing Paroxysmal Sympathetic Hyperactivity in Patients with Traumatic Brain Injury

机译：血清procalcitonin在创伤性脑损伤患者患者阵发性交感神经中的效用

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Background:Paroxysmal sympathetic hyperactivity (PSH) is a grave entity affecting patients following traumatic brain injury (TBI). It presents with cyclic and simultaneous fever, posturing, and other symptoms of sympathetic hyperactivity. Lack of diagnostic tests or biochemical markers and its propensity to mimic other common causes of fever in the neurotrauma intensive care unit (ICU) result in clinical dilemmas and management delay.Case Descriptions:We present a case series of four patients (two adults and two pediatrics) with TBI who developed PSH during ICU stay. These patients presented with fever along with variable symptoms of sympathetic hyperactivity. However, the value of serum procalcitonin (PCT) was not elevated, and management of PSH was started. Serial monitoring of PCT helped in differentiating fever due to PSH from sepsis and thus the institution of appropriate and timely treatment of PSH and also helped to use antibiotics rationally.Conclusion:The use of serum PCT in differentiating sepsis from systemic inflammatory reaction and its role in the initiation and titration of antibiotics are well described. PSH is a common entity after TBI, causing episodic fever and sympathetic hyperactivity, often confused with infectious pathology. Our report proposes the role of serum PCT in differentiating PSH from infectious etiology and management of two different clinical entities.How to cite this article:Bindra A, Chowdhary V, Dube SK, Goyal K, Mathur P. Utility of Serum Procalcitonin in Diagnosing Paroxysmal Sympathetic Hyperactivity in Patients with Traumatic Brain Injury. Indian J Crit Care Med 2021;25(5):580-583.Copyright ? 2021; Jaypee Brothers Medical Publishers (P) Ltd.
机译：背景：阵发性交感神经（PSH）是一种严重的实体，影响患有创伤性脑损伤（TBI）后的患者。它呈现出循环和同时发热，姿势和交感神经多动症的其他症状。缺乏诊断测试或生物化学标记及其模仿其他常见发烧的倾向，即神经统计学重症监护病房（ICU）导致临床困境和管理延迟。Case描述：我们出示了一个案例系列的四名患者（两个成年人和两个儿科学系统）与TBI在ICU逗留期间开发了PSH。这些患者发烧以及可变症状的交感神经症状。但是，血清ProCalcitonin（PCT）的价值未提升，并开始管理PSH。 PCT的连续监测有助于败血症的分化发烧，因此适当及时治疗PSH的制度，也有助于使用抗生素。结论：使用血清PCT在将败血症中的使用与全身炎症反应区分不同及其作用抗生素的起始和滴定很好地描述。 PSH是TBI后的常见实体，导致情节发烧和交感神经过度，通常与传染病感到混淆。我们的报告提出了血清PCT在分化两种不同临床实体的传染病学和管理中的作用。引用本文：Bindra A，Chowdhary V，Dube SK，Goyal K，Mathur P.血清ProCalcitonin诊断阵发性诊断创伤性脑损伤患者的交感神经活跃。印度j crit care med 2021; 25（5）：580-583.copyright？ 2021; Jaypee Brothers Medical Publishers（P）有限公司

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