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首页> 外文期刊>OTO Open >Association of Race/Ethnicity, Stage, and Survival in Oral Cavity Squamous Cell Carcinoma: A SEER Study
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Association of Race/Ethnicity, Stage, and Survival in Oral Cavity Squamous Cell Carcinoma: A SEER Study

机译：种族/种族，阶段和口腔鳞状细胞癌中的生存协会：SEER研究

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Objective. Survival differences in oral cancer between black and white patients have been reported, but the contributing factors, especially the role of stage, are incompletely understood. Furthermore, the outcomes for Hispanic and Asian patients have been scarcely examined. Study Design. Retrospective, population-based national study. Setting. Surveillance, Epidemiology, and End Results 18 Custom database (January 1, 2010, to December 31, 2014). Subjects and Methods. In total, 7630 patients with primary squamous cell carcinoma in the oral cavity were classified as non-Hispanic white (white), non-Hispanic black (black), Hispanic, or Asian. Cox regression was used to obtain unadjusted and adjusted hazard ratios (HRs) of 5-year mortality for race/ethnicity with sequential adjustments for stage and other covariates. Logistic regression was used to examine the relationship between race/ethnicity and stage with adjusted odds ratios (aORs). Results. The cohort consisted of 75.0% whites, 7.6% blacks, 9.1% Hispanics, and 8.3% Asians. Compared to whites, the unadjusted HR for all-cause mortality for blacks was 1.68 (P .001), which attenuated to 1.15 (P = .039) after adjusting for stage and became insignificant after including insurance. The unadjusted HRs for all-cause mortality were not significant for Hispanics and Asians vs whites. Compared to whites, blacks and Hispanics were more likely to present at later stages (aORs of 2.63 and 1.42, P .001, respectively). Conclusion. The greater mortality for blacks vs whites was largely attributable to the higher prevalence of later stages at presentation and being uninsured among blacks. There was no statistically significant difference in mortality for Hispanics vs whites or Asians vs whites.
机译：客观的。报告了黑白患者之间口腔癌的存活差异，但贡献因素，尤其是阶段的作用是不完全理解的。此外，患有西班牙裔和亚洲患者的结果几乎没有检查过。学习规划。回顾性，基于人口的国家研究。环境。监测，流行病学和最终结果18定制数据库（2010年1月1日至2014年12月31日）。主题和方法。总共有7630名口腔中鳞状细胞癌的患者被归类为非西班牙裔（白色），非西班牙裔（黑色），西班牙裔或亚洲人。 COX回归用于获得比赛/种族的5年死亡率的未经调整和调整的危险比（HRS），阶段和其他协变量的顺序调整。 Logistic回归用于检查种族/种族和阶段之间的关系，调整后的赔率比（AOR）。结果。队列由75.0％的白人，7.6％黑人，9.1％西班牙裔和8.3％的亚洲人组成。与白人相比，黑人的所有原因死亡率的不调整的人力资源为1.68（p .001），在调整阶段后衰减至1.15（p = .039），包括保险后变得微不足道。所有原因死亡率的未经调整的人力资源对西班牙裔和亚洲人vs白人并不重要。与白人相比，黑人和西班牙裔更有可能在以后的阶段（分别为2.63和1.42，P .001）。结论。黑人对黑人的死亡率较大，在呈现的阶段的较高阶段的普遍性较高，并且在黑人中没有保险。西班牙裔人和白人或亚洲人对白人的死亡率没有统计学意义。

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