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Coeliac Disease: A Subtle yet Life Changing Diagnosis

机译:乳糜泻:一个微妙的但生活不断变化的诊断

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Coeliac disease is an autoimmune condition where the small intestine becomes damaged with ingestion of gluten (present in wheat, barley, and rye) (1). Despite it being a common condition with a global prevalence of 1.4% (2), the vast majority of patients remain undiagnosed (3). It is thought that the difficulty in its diagnosis is due to its variable presentation, as not all patients have the classic symptoms like diarrhea or abdominal pain but may solely have extraintestinal symptoms (4). Undiagnosed and untreated coeliac disease is associated with the development of osteoporosis, infertility, further autoimmune conditions, and cancer (5).
机译:乳糜泻是一种自身免疫性条件,小肠因摄入麸质而受损(在小麦,大麦和黑麦中存在)(1)。 尽管它是全球患病率为1.4%(2)的常见条件,但绝大多数患者仍未结束(3)。 据认为,其诊断的困难是由于其变量呈现,而不是所有患者都有腹泻或腹痛等经典症状,但可能仅仅具有肾外症状(4)。 未结社和未经处理的乳糜泻与骨质疏松症,不孕症,进一步的自身免疫病症和癌症(5)有关。

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