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Cost Analysis of FreeStyle Libre??2 System in Type?2 Diabetes Mellitus Population

机译：自由式Libre的成本分析？2型糖尿病群体的2系统

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IntroductionFreeStyle Libre ? ?2?system is a sensor-based flash-monitoring system that measures interstitial fluid glucose. The study aimed to compare cost of FreeStyle Libre 2 system and self-monitoring of blood glucose (SMBG) in the type?2 diabetes mellitus (T2DM) population from the Spanish Health System perspective.MethodsOn the basis of data collected from a literature review, the cost of glucose monitoring was modelled for patients with T2DM on a basal-bolus insulin regimen. The cost estimate included annual consumption for glucose monitoring (strips, lancets and sensors) and severe hypoglycaemic events (SHE) management. A published rate of SHE (2.5?episodes/patient-year) was considered. A reduction of SHE (? 48.8%) associated with FreeStyle Libre 2 system, derived from the REPLACE trial, was applied. Hospital attendance for 20.5% of SHEs (with subsequent hospitalization in 16.0%) was applied. Consumption of strips and lancets was set at 6/day for SMBG (derived from national monitoring recommendations), and 0.2/day for FreeStyle Libre 2 system users, with 26?FreeStyle Libre 2 sensors/year. Unitary costs (€, year 2020 excluding VAT) were derived from literature (€0.28/strip; €0.09/lancet; €3.09/daily FM sensor; €3804/hospitalized SHE; €1794/hospital-attended non-admitted SHE; €389/community-attended SHE).ResultsCosts were €2700 and €2120/year/patient using SMBG or FreeStyle Libre 2 system, respectively. For 1000 patients with T2DM using basal-bolus insulin, 1220?SHEs/year (with 48 hospitalizations) could be prevented and FreeSytle Libre 2 system could generate cost savings of up to €580,953/year versus SMBG (??21.5%).Conclusion FreeStyle Libre 2 system is a potential cost-saving strategy in patients with T2DM in Spain on a basal-bolus insulin regimen.
机译：介绍夫利libre？ ？2？系统是一种基于传感器的闪光监测系统，测量间质性流体葡萄糖。该研究旨在比较自由式Libre 2系统的成本，以及来自西班牙卫生系统透视的2型糖尿病（T2DM）人群的血糖（SMBG）的自我监测。方法从文献综述中收集的数据的基础，葡萄糖监测成本为基础推注胰岛素方案的T2DM患者进行了模拟。成本估算包括葡萄糖监测（条带，血管和传感器）的年消耗和严重的低血糖事件（她）管理。审议了她（2.5？剧集/患者年）的公布率。应用与替换试验的自由式Libre 2系统相关的她（？48.8％）的减少。申请了20.5％的医院出席（随后的住院治疗16.0％）。 SMBG（来自国家监测建议的SMBG（来自国家监测建议）的6 /天设定了3 /天的消费，为自由式Libre 2系统用户提供了0.2天，有26个？自由式Libre 2传感器/年。统一成本（欧元，2020年不包括增值税）来自文献（€0.28 /€;€0.09 /刺血液;€3.09 /每日FM传感器;€3804 /住院她;€1794 / Hospital-inuchare-出席的非承认她;€ 389 /社区 - 出席了她）.Resultscosts分别使用SMBG或Freestyle Libre 2系统分别为2700欧元和2120欧元/患者。对于1000例T2DM患者使用基础推子胰岛素，1220？SHES /年（附属48个住院）可以防止，并且FreeSytle Libre 2系统可以节省高达580,953欧元/年与SMBG（21.5％）的成本节省。结论自由式Libre 2系统是西班牙T2DM患者患者的潜在节省成本策略。

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