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首页> 外文期刊>Bangladesh Journal of Plant Taxonomy >Thrombolytic Potentials of Some Medicinal Plants Used by the Local People for Cardiovascular Diseases in Bangladesh
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Thrombolytic Potentials of Some Medicinal Plants Used by the Local People for Cardiovascular Diseases in Bangladesh

机译：孟加拉国局部人民用心血管疾病使用的一些药用植物的溶栓潜力

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摘要

Cardiovascular diseases (CVDs) are one of the major causes of death in the world. Medicinal plants with thrombolytic properties may be used as an alternative to modern medicines for CVDs. The present study was aimed to evaluate the thrombolytic potential of six medicinal plants available in Bangladesh using an in vitro clot lysis method where streptokinase and ethanol were used as a positive and negative control, respectively. Ethanolic extract at a dose of 10 mg/ml of Arjun tree (Terminalia arjuna), Garlic (Allium sativum), Elephant apple (Dillenia indica), Amla (Phyllanthus emblica), Yellow mombin (Spondias pinnata) and Burmese grape (Baccaurea ramiflora) showed 14.18 ± 1.23%, 10.72 ± 0.78%, 8.25 ± 0.42%, 7.08 ± 0.64%, 5.42 ± 0.47% and 2.47 ± 0.19% clot lysis, respectively, whereas the standard drug streptokinase lysed 41.11±0.31% clot at a dose of 30,000 IU. From the data, it is evident that ethanolic extracts of six selected medicinal plants possess a moderate to insignificant thrombolytic activities. Among these plants, Arjun tree and Garlic exhibited the highest thrombolytic activity and the Burmese grape showed the lowest thrombolytic activity. Through our study, it could be concluded that Arjun tree, Garlic, and Elephant apple might be used as traditional healing purposes of CVDs. However, further animal studies will prove the scientific justification of their uses. Conservation efforts should be given for Arjun tree, Elephant apple, Yellow mombin, Burmese grape, and Amla to save these plants from extinction in nature.
机译：心血管疾病（CVDS）是世界上死亡的主要原因之一。具有溶栓性性质的药用植物可作为CVDS的现代药物用作替代品。本研究旨在使用体外凝块裂解方法评估孟加拉国六种药用植物的溶栓潜力，分别使用链激酶和乙醇作为正和阴性对照。乙醇提取物的剂量为10 mg / ml Arjun树（Termantia Arjuna），大蒜（Allium sativum），大象苹果（Dillenia indica），Amla（Phyllanthus emblica），黄色蒙宾（纯粹的Pinnata）和缅甸葡萄（Baccaurea ramiflora）显示14.18±1.23％，10.72±0.78％，8.25±0.42％，分别为708±0.64％，分别为5.42±0.47％和2.47±0.19％凝块裂解，而标准药物链激酶裂解为剂量的41.11±0.31％凝块30,000 IU。从数据中，显然，六种选定的药用植物的乙醇提取物具有中度至微不足道的血栓形成活性。在这些植物中，Arjun树和大蒜表现出最高的血栓溶液活性，并且缅甸葡萄显示出最低的血栓溶液活性。通过我们的研究，可以得出结论，Arjun树，大蒜和大象苹果可能被用作CVDS的传统治疗目的。然而，进一步的动物研究将证明他们的用途的科学理由。应为Arjun树，大象苹果，黄蒙宾，缅甸葡萄和Amla提供保护努力，以拯救这些植物在自然界中灭绝。

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