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Sclerotherapy with Leuprolide and Cefoperazone Sulbactam in the Management of Ovarian Endometriomas under Ultrasound Guidance: A Novel Approach

机译:在超声引导下,用血红蛋白和头孢唑唑胺的硬化疗法在卵巢子宫内膜瘤管理中:一种新的方法

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Endometriosis is an estrogen dependent gynecological disorder, which can occur throughout the reproductive age of women, causing chronic pelvic pain, substantial morbidity, and impaired fertility. It is clinically defined as the presence of ectopic endometrium resulting in sustained inflammatory reaction. In India , about 29,000,000 women suffer from endometriosis. Severe pelvic pain and recurrent endometriomas were observed even after surgery. We have conducted aspirations totally in 110 patients in which most of the patients were suffering from Stage III & Stage IV of endometriosis except for 7 patients for whom we have done as primary therapy for endometriomas. Among 110 patients , 4 patients didn’t turn up for follow up after first aspiration. This pilot study conducted with 110 patients in Ponni Hospital and Fertility Research Centre, Madurai aimed to evaluate pregnancy outcome in 51 infertile patients, and to alleviate pelvic pain, to restore a healthy sexual life and to reduce the recurrence rate of Ovarian Endometriomas (OE) in 59 patients, who did not seek fertility, After using the newer sclerosing agent Leuprolide with Cefoperazone Sulbactam (LCS) under ultrasound guidance. This prospective pilot study resulted in a highly significant achievement in pregnancy where 41 patients conceived out of 51 patients (80.39%) only 6 are in ongoing treatment. Those who didn’t seek fertility were 59 of which 43 have completed family 1 3 have one child and 3 unmarried girls . 96.61% were relieved of pain and recurrence and restored healthy sexual life, 2 are in ongoing treatment. We have not encountered any adverse effects during this treatment.
机译:子宫内膜异位症是一种雌激素依赖性妇科疾病,其在整个妇女的生殖年龄可能发生,导致慢性盆腔疼痛,大量发病率和生育受损。临床定义为异位子宫内膜的存在,导致持续的炎症反应。在印度,约29,000,000名女性患有子宫内膜异位症。甚至在手术后,均甚至观察到严重的盆腔疼痛和复发子宫内膜异构瘤。我们在110名患者中进行了愿望,其中大多数患者患有III阶段患者。子宫内膜异位症阶段IV除了7名患者,我们为子宫内膜异构瘤做的主要疗法。在110名患者中,4名患者在首次愿望后没有出现随访。该试点研究了Madurai的Ponni医院和生育研究中心的110名患者,旨在评估51名不孕症患者的怀孕结果,并减轻骨盆疼痛,恢复健康的性生活,并降低卵巢子宫内膜瘤的复发率(OE)在59名患者中,在超声引导下使用较新的硬化剂嗜血酰胺(LCS)使用较新的硬化剂嗜血泡(LCS)之后。这项前瞻性试点研究导致怀孕的高度显着成就,其中41名患者患有51名患者(80.39%)仅在持续治疗中。那些没有寻求生育的人是59个,其中43家已完成的家庭1 3有一个孩子和3个未婚女孩。 96.61%的痛苦和复发性和恢复健康的性生活,2是在持续治疗中的痛苦和复发。在这种治疗期间,我们没有遇到任何不利影响。

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