Polysaccharide based polymers are widely used inbiomedical applications. In this study, nanofibrous mat was produced fromhyaluronic acid, carboxymethyl cellulose and sodium alginate polysaccharide polymersvia electrospinning method. Resultant nanofibrous mat was crosslinked with 1-etil-3-(3-dimethylaminopropyl)carbodiimide hydrochloride and N-hydroxysulfosuccinimidesolution to develop its water resistance. Before and after the crosslinkingprocess, nanofibrous mat was characterized by scanning electron microscope,fourier transform infrared spectrometry, atomic force microscope, BET analysis andwater resistance test. The resultsindicated that the nanofibrous mat was become resistant to water without anydeformation of nanofibrous structure with the crosslinking application.
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