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Diet, Nutrition, Obesity, and Their Implications for COVID-19 Mortality: Development of a Marginalized Two-Part Model for Semicontinuous Data

机译:饮食,营养,肥胖,以及对Covid-19死亡率的影响:开发半连续数据的边缘化两部分模型

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Background Nutrition is not a treatment for COVID-19, but it is a modifiable contributor to the development of chronic disease, which is highly associated with COVID-19 severe illness and deaths. A well-balanced diet and healthy patterns of eating strengthen the immune system, improve immunometabolism, and reduce the risk of chronic disease and infectious diseases. Objective This study aims to assess the effect of diet, nutrition, obesity, and their implications for COVID-19 mortality among 188 countries by using new statistical marginalized two-part models. Methods We globally evaluated the distribution of diet and nutrition at the national level while considering the variations between different World Health Organization regions. The effects of food supply categories and obesity on (as well as associations with) the number of deaths and the number of recoveries were reported globally by estimating coefficients and conducting color maps. Results The findings show that a 1% increase in supplementation of pulses reduced the odds of having a zero death by 4-fold (OR 4.12, 95% CI 11.97-1.42). In addition, a 1% increase in supplementation of animal products and meat increased the odds of having a zero death by 1.076-fold (OR 1.076, 95% CI 1.01-1.15) and 1.13-fold (OR 1.13, 95% CI 1.0-1.28), respectively. Tree nuts reduced the odds of having a zero death, and vegetables increased the number of deaths. Globally, the results also showed that populations (countries) who consume more eggs, cereals excluding beer, spices, and stimulants had the greatest impact on the recovery of patients with COVID-19. In addition, populations that consume more meat, vegetal products, sugar and sweeteners, sugar crops, animal fats, and animal products were associated with more death and less recoveries in patients. The effect of consuming sugar products on mortality was considerable, and obesity has affected increased death rates and reduced recovery rates. Conclusions Although there are differences in dietary patterns, overall, unbalanced diets are a health threat across the world and not only affect death rates but also the quality of life. To achieve the best results in preventing nutrition-related pandemic diseases, strategies and policies should fully recognize the essential role of both diet and obesity in determining good nutrition and optimal health. Policies and programs must address the need for change at the individual level and make modifications in society and the environment to make healthier choices accessible and preferable.
机译:背景技术营养不是Covid-19的治疗,但它是一种可修改的慢性疾病发展的贡献者,这与Covid-19严重疾病和死亡高度相关。均衡的饮食和健康模式加强免疫系统,改善免疫素质,降低慢性疾病和传染病的风险。目的本研究旨在评估饮食,营养,肥胖症的影响,通过使用新的统计边缘化两部分模型来评估188个国家之间对Covid-19死亡率的影响。方法在考虑不同世界卫生组织地区之间的变化,我们在全球范围内评估了国家一级的饮食和营养的分布。通过估计系数和进行颜色地图,全球粮食供应类别和肥胖的影响(以及协会的协会)的影响和回收率的次数。结果结果表明,脉冲补充的1%增加降低了4倍(或4.12,95%CI 11.97-1.42)的零死亡的几率。此外,对动物产品和肉类补充的1%增加增加了零死亡的几率为1.076倍(或1.076,95%CI 1.01-1.15)和1.13倍(或1.13,95%CI 1.0- 1.28)分别。树坚果降低了零死亡的几率,蔬菜增加了死亡人数。在全球范围内,结果还表明,消耗更多鸡蛋,除了啤酒,香料和兴奋剂不包括啤酒,香料和兴奋剂的谷物的人口(国家)对Covid-19患者的回收产生了最大的影响。此外,消耗更多肉类,植物产品,糖和甜味剂,糖作物,动物脂肪和动物产品的种群与更多的死亡和患者的回收率较少有关。消耗糖产物对死亡率的影响是相当大的,肥胖影响了死亡率增加和恢复率降低。结论虽然饮食模式存在差异,但总体而言,不平衡的饮食是世界各地的健康威胁,而且不仅影响死亡率,而且影响生活质量。为了实现预防营养相关的大流行病的最佳结果,策略和政策应充分认识到饮食和肥胖在确定良好的营养和最佳健康方面的基本作用。政策和计划必须解决个人级别变更的必要性,并在社会和环境中进行修改,以使更健康的选择可以获得和优选。

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