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Czech Childhood Cancer Information System: Data Analysis and Interactive Visualisation

机译:捷克儿童癌症信息系统:数据分析和交互式可视化

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Background The knowledge of cancer burden in the population, its time trends, and the possibility of international comparison is an important starting point for cancer programs. A reliable interactive tool describing cancer epidemiology in children and adolescents has been nonexistent in the Czech Republic until recently. Objective The goal of this study is to develop a new web portal entitled the Czech Childhood Cancer Information System (CCCIS), which would provide information on childhood cancer epidemiology in the Czech Republic. Methods Data on childhood cancers have been obtained from the Czech National Cancer Registry. These data were validated using the clinical database of childhood cancer patients and subsequently combined with data from the National Register of Hospitalised Patients and with data from death certificates. These validated data were then used to determine the incidence and survival rates of childhood cancer patients aged 0 to 19 years who were diagnosed in the period 1994 to 2016 (N=9435). Data from death certificates were used to monitor long-term mortality trends. The technical solution is based on the robust PHP development Symfony framework, with the PostgreSQL system used to accommodate the data basis. Results The web portal has been available for anyone since November 2019, providing basic information for experts (ie, analyses and publications) on individual diagnostic groups of childhood cancers. It involves an interactive tool for analytical reporting, which provides information on the following basic topics in the form of graphs or tables: incidence, mortality, and overall survival. Feedback was obtained and the accuracy of outputs published on the CCCIS portal was verified using the following methods: the validation of the theoretical background and the user testing. Conclusions We developed software capable of processing data from multiple sources, which is freely available to all users and makes it possible to carry out automated analyses even for users without mathematical background; a simple selection of a topic to be analyzed is required from the user.
机译:背景技术人口中癌症负担,其时间趋势以及国际比较的可能性是癌症计划的重要起点。捷克共和国的一个可靠的互动工具,描述儿童和青少年的癌症流行病学直到最近一直不存在。目的是该研究的目标是开发一个题为捷克儿童癌症信息系统(CCCIS)的新网站门户网站,这将提供捷克共和国儿童癌症流行病学的信息。方法已从捷克国家癌症登记处获得儿童癌症的数据。使用儿童癌症患者的临床数据库进行验证这些数据,随后与来自住院患者的国家登记册和死亡证书数据的数据结合。然后用于确定1994年至2016年期间诊断的儿童癌症患者的患者癌症患者的发生率和存活率(n = 9435)。来自死亡证明书的数据用于监测长期死亡率趋势。技术方案基于强大的PHP开发symfony框架,PostgreSQL系统用于适应数据。结果自2019年11月以来的任何人都可以提供网络门户,为儿童癌症的个体诊断群体提供专家(即分析和出版物)的基本信息。它涉及分析报告的交互式工具,它提供了关于图形或表格形式的以下基本主题的信息:发病率,死亡率和整体存活。获得了反馈并使用以下方法验证了CCCIS门户上发布的输出的准确性:验证理论背景和用户测试。结论我们开发了能够从多个来源处理数据的软件,这是对所有用户自由使用的数据,并使即使对于没有数学背景的用户,也可以进行自动分析;用户需要简单的选择要分析的主题。

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