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首页> 外文期刊>Journal of International Medical Research >Clinical outcomes for Day 3 double cleavage-stage embryo transfers versus Day 5 or 6 single blastocyst transfer in frozen–thawed cycles: a retrospective comparative analysis
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Clinical outcomes for Day 3 double cleavage-stage embryo transfers versus Day 5 or 6 single blastocyst transfer in frozen–thawed cycles: a retrospective comparative analysis

机译：第3天的临床结果双重切割阶段胚胎转移与冷冻循环中的第5天或6个单胚性转移：回顾性比较分析

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Objective This study aimed to compare the clinical outcomes for transfer of Day 3 (D3) double cleavage-stage embryos and Day 5/6 (D5/6) single blastocysts in the frozen embryo transfer (FET) cycle to formulate a more appropriate embryo transplantation strategy. Methods We retrospectively analyzed 609 FET cycles from 518 women from April 2017 to March 2021. All FETs were assigned to the D3-DET group (transfer of a Day 3 double cleavage-stage embryo), D5-SBT group (transfer of a Day 5 single blastocyst), or D6-SBT group (transfer of a Day 6 single blastocyst). Clinical outcomes were comparatively analyzed. Results There were no significant differences in the biochemical pregnancy rate, clinical pregnancy rate, or ongoing pregnancy rate between the D3-DET and D5-SBT groups, but these rates in the two groups were all significantly higher compared with those in the D6-SBT group. The implantation rate in the D5-SBT group was significantly higher than that in the D3-DET group. The twin pregnancy rate in the D5-SBT and D6-SBT groups was significantly lower than that in the D3-DET group. Conclusion This study suggests that D5-SBT is the preferred option for transplantation. D6-SBT reduces the pregnancy rate, making it a more cautious choice for transfer of such embryos.
机译：目的本研究旨在比较冷冻胚胎转移（FET）循环中的第3天（D3）双切割阶段胚胎和第5/6天（D5 / 6）单胚泡的临床结果，以制备更合适的胚胎移植战略。方法方法从2017年4月至3月2021年度回顾性分析了518名妇女的609次FET周期。所有FET分配给D3-DEC组（转移一天三次双切割阶段胚胎），D5-SBT组（转移第5天单胚泡）或D6-SBT组（转移6天单胚泡）。临床结果比较分析。结果D3-DET和D5-SBT组之间的生化妊娠率，临床妊娠率或持续妊娠率无显着差异，但与D6-SBT中的两组中的这些速率相比，两组的速率明显高得多团体。 D5-SBT组中的植入率明显高于D3-DET组中的植入率。 D5-SBT和D6-SBT组中的双妊娠率明显低于D3-DEC组。结论本研究表明D5-SBT是移植的首选选择。 D6-SBT降低了怀孕率，使其更加谨慎地转移这种胚胎。

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