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Data from small cell neuroendocrine carcinoma of the cervix: FIGO 2018 staging is more accurate than FIGO 2009

机译:来自宫颈小细胞神经内分泌癌的数据:FIGO 2018分期比FIGO 2009更准确

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Objective To compare the prognostic value of International Federation of Gynecology and Obstetrics (FIGO) 2009 and 2018 staging systems in surgical patients with small cell neuroendocrine carcinoma of the cervix (SCNEC). Methods We re-staged 64 surgical IB–IIA (FIGO 2009) SCNEC patients according to the FIGO 2018 system and refined stage IIIC of FIGO 2018 based on tumor local invasion. The prognostic factors were analyzed, and the advantages of FIGO 2018 were compared with 2009. Results The 5-year overall survival rate (OS) was 78.5% for stage I and 22.2% for stage II (FIGO 2009). In FIGO 2018, there was no difference between stage I and II, and the 5-year OS was 74.1%, 60.2%, and 0% for stage I/II, IIIC1, and IIIC2. After combining stage IIIC with the local invasion stage (T1 was limited to the cervix and vagina; T2 involved the parametrium; T3 involved the pelvic or abdominal cavity), the 5-year OS for stage IIICT1, IIICT2, and IIICT3 was 83.3%, 30.0%, and 0%, respectively. Conclusions For stage II SCNEC patients, FIGO 2009 underestimated the prognosis, while FIGO 2018 was more accurate. For stage IIIC, FIGO 2018 might be more individualized and accurate after combining stage IIIC with tumor local invasion.
机译:目的比较国际妇科和产科联合会(FICO)2009和2018年宫颈癌(SCNEC)小细胞神经内分泌癌的手术患者中的预后价值。方法根据肿瘤局部入侵,我们重新分阶段64个外科IB-IIA(FIGO 2009)SCNEC患者和FIGO 2018的精致阶段IIIC。分析了预后因素,与2009年进行了比较2018年的优势。结果,5年的总生存率(OS)为阶段I的78.5%,阶段II的22.2%(FIGO 2009)。在2018年,阶段I和II之间没有差异,5年的OS为阶段I / II,IIIC1和IIIC2的74.1%,60.2%和0%。将IIIC阶段与局部侵入阶段(T1仅限于子宫颈和阴道; T2涉及参数; T3涉及盆腔或腹腔),第IIICT 1,IIICT2和IIICT3阶段的5年OS为83.3%, 30.0%和0%。结论II阶段SCNEC患者,FIGO 2009低估了预后,而FIGO 2018更准确。对于IIIC,FIGO 2018可能在与肿瘤局部侵袭组合II阶段后更表格和准确。

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