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首页> 外文期刊>Journal of International Medical Research >Comparison of invasive intubation and noninvasive mechanical ventilation in patients with chronic obstructive pulmonary disease and obstructive sleep apnoea syndrome
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Comparison of invasive intubation and noninvasive mechanical ventilation in patients with chronic obstructive pulmonary disease and obstructive sleep apnoea syndrome

机译：慢性阻塞性肺病患者侵入性插管和非侵入机械通气的比较及阻塞性睡眠呼吸暂停综合征

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Objective The concurrence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea syndrome (OSAS) is defined as overlap syndrome (OS), but investigations into predictors of OS in patients with COPD remain limited. Here, potential markers of OS in patients with COPD were investigated, and results of intubation were compared between patients with COPD only or OS. Methods This retrospective study included patients with COPD who were divided according to OS diagnosis: COPD only (COPD group) or OS (OS group). Results Among 206 patients with COPD, 120 were diagnosed with OS. Mean body mass index (BMI) was significantly higher in the OS versus COPD group (28.95 ± 2.96 versus 23.84 ± 4.06, respectively). Receiver operating characteristic curve analyses revealed that BMI was associated with OS (area under the curve, 0.835). The rate of invasive intubation within 48 h was lower in the OS versus COPD group (9.2% versus 20.9%, respectively), and the duration of noninvasive ventilation was longer in the OS versus COPD group. Conclusions BMI may be a predictor of OS in patients with COPD. The duration of noninvasive ventilation was longer in patients with OS than in patients with COPD alone.
机译：目的慢性阻塞性肺疾病（COPD）和阻塞性睡眠呼吸暂停综合征（OSAs）的同意定义为重叠综合征（OS），但研究COPD患者患者的OS预测因子仍然有限。在此，研究了COPD患者的OS的潜在标志物，并且在仅COPD或OS的患者之间比较了插管的结果。方法本回顾性研究包括根据OS诊断分割的COPD患者：仅限COPD（COPD组）或OS（OS组）。结果206例COPD患者，120名患者被诊断为OS。 OS与COPD组的平均体重指数（BMI）显着高于28.95±2.96分别与23.84±4.06）。接收器操作特征曲线分析显示BMI与OS（曲线下的面积，0.835）相关。 OS与COPD组的48小时内的侵入性插管率较低（分别为9.2％，分别为20.9％），并且在OS与COPD组中的非侵入性通气持续时间更长。结论BMI可能是COPD患者OS的预测因子。 OS患者的非侵入性通气的持续时间比单独的COPD患者更长。

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