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A rare form of intoxication: acute methyl ethyl ketone peroxide poisoning

机译:一种罕见的中毒形式:急性甲基乙基酮过氧化物中毒

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We report two suicidal cases of acute methyl ethyl ketone peroxide (MEKP) poisoning. A woman in her late 60s suffered from oral mucosal erosion, functional impairment of the heart, liver and other organs, pulmonary inflammation, elevated inflammatory markers, pleural effusion, hypoproteinemia and metabolic acidosis after oral administration of approximately 50?mL of MEKP. After admission, the patient was administered hemoperfusion four times, 8?mg of betamethasone for 6 days and symptomatic support. Hemoperfusion had an obvious effect on the treatment of oral MEKP poisoning. After discharge, the patient developed progressive dysphagia and secondary esophageal stenosis. Supplementary feeding was administered with a gastrostomy tube after the patient was completely unable to eat. A man in his mid-40s developed oropharyngeal mucosal erosion, bronchitis and esophageal wall thickening after oral administration of 40?ml MEKP. After receiving total gastrointestinal dispersal, 80?mg of methylprednisolone was administered for 7 days, and symptomatic supportive treatment was provided. Slight dysphagia was observed after discharge, and there was no major effect on the quality of life. Patients with acute oral MEKP poisoning should be followed up regularly to observe its long-term effects on digestive tract corrosion and stenosis.
机译:我们报告了两种急性甲基乙基酮过氧化物(MEKP)中毒的自杀案例。 60年代后期的一个女人患有口腔粘膜糜烂,心脏,肝脏等器官,肺炎炎,炎症,血液施用约50μmmmmm克服后的抗炎症,炎症,炎症标志物,胸腔积液,缺血性血症和代谢酸中毒的功能障碍。入院后,将患者施用血液灌注4次,8μmg倍甲塞松6天和症状。血液灌注对口腔颌面中毒的治疗有明显影响。放电后,患者发育了渐进式吞咽和继发性食管狭窄。在患者完全无法吃后,用胃造口管施用补充饲料。在他40岁的40岁中间的一个人开发了口咽粘膜糜烂,支气管炎和口服给药后的食管壁增厚40?ml MEKP。在接受总胃肠道分散后,给药80μg甲基己酮酮7天,并提供症状支撑治疗。出院后观察到轻微的吞咽症,对生活质量没有重大影响。应定期随访急性口腔患者,观察其对消化道腐蚀和狭窄的长期影响。

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