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首页> 外文期刊>Journal of International Medical Research >Comprehensive meta-analysis of associations between temperament and character traits in Cloninger’s psychobiological theory and mental disorders
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Comprehensive meta-analysis of associations between temperament and character traits in Cloninger’s psychobiological theory and mental disorders

机译：克朗林格心理学理论与精神障碍的气质和性格特征之间的综合荟萃分析

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Objective To explore the relationship between temperament and character traits in Cloninger’s psychobiological theory and mental disorders. Method s: A systematic literature search was conducted of five international databases for all articles published in English between January 1990 and April 2019 (PROSPERO-CRD42019133214). Owing to heterogeneity, pooled estimates of correlations for personality disorders and standardized mean differences for case–control studies related to other mental disorders were calculated using the random-effects method. Results The pooled effect sizes obtained from 149 studies showed that high harm avoidance (related to 22/24 diagnostic categories), low self-directedness (21/23), low cooperativeness (17/23), high self-transcendence (14/23), low reward dependence (11/24), high novelty-seeking (10/24), low novelty-seeking (7/24), high persistence (2/23), low persistence (2/23) and high reward dependence (2/24) were related to psychopathology. Conclusions All traits provided unique psychobiological tools for differential diagnosis of mental disorders. However, high harm avoidance and low self-directedness played a canonical role in psychopathology. Despite the study limitations, additional studies are warranted to evaluate the differential diagnoses suggested by the present model.
机译：目的探讨克朗林格心理学理论与精神障碍的气质与性格特征的关系。方法S：1990年1月至2019年1月至2019年4月（Prospero-CRD42019133214）的所有文章进行了系统文献搜索。由于异质性，使用随机效应法计算了与其他精神障碍有关的人格障碍的相关性和标准化平均差异的汇总估计。结果149项研究中获得的汇总效应大小表明，高危害避免（与22/24诊断类别相关），低自我导向（21/23），低合作（17/23），高自我超越（14/23） ），低奖励依赖（11/24），高新程序（10/24），新颖性寻求（7/24），高持久性（2/23），低持久性（2/23）和高奖励依赖（2/24）与精神病理学有关。结论所有特征都提供了独特的精神病学工具，用于鉴别诊断精神障碍。然而，高危害避免和低自我导向在精神病理学中起着规范作用。尽管研究局限性，但额外的研究是值得评估本模型所建议的差异诊断。

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