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Estimating the minimal clinically important difference for the Physical Component Summary of the Short Form 36 for patients with stroke

机译：脑卒中患者估算短表36的物理成分概要的最小临床重要差异

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Objective To determine the Physical Component Summary (PCS) score's minimal clinically important difference (MCID) on the Short Form 36 (SF-36) for people with stroke. Methods We conducted secondary analysis of data from a large randomized controlled trial (N?=?400) in the post-hospital discharge phase of stroke rehabilitation with outcome measurement 6 and 12 months following stroke. Three methods were used for estimating the MCID: two anchor and one distribution. Method 1 compared SF-36 PCS scores at 12 months for responses to the SF-36’s Perceived Health Change (PHC) question. Method 2 compared the change in PCS score between 6 and 12 months for responses to the PHC question. Method 3 used Cohen’s method to estimate the MCID from the PCS score distribution. Results Method 1: the mean PCS score increased by 3.0 units (95% confidence interval [CI] 2.2–3.9) for each unit change in the PHC question. Method 2: the mean change in PCS score increased by 2.1 units (95% CI 1.4–2.8) for each unit change in the PHC question. Method 3: the MCID was estimated to be 1.8 units. Conclusions Our estimate of the MCID for the PCS in patients with stroke was 1.8 to 3.0 units.
机译：目的确定具有中风的人的短型36（SF-36）的短表36（SF-36）的最小临床重要差异（MCID）。方法在中风后6和12个月，我们在医院后医院排放阶段的大型随机对照试验（N？= 400）中的数据进行了二次分析。三种方法用于估计MCID：两个锚和一个分布。方法1在12个月比较SF-36 PCS分数，以应对SF-36的感知健康变化（PHC）问题。方法2将PCS分数的变化与6至12个月之间的变化进行了响应，以便对PHC问题进行响应。方法3使用COHEN的方法从PCS得分分布中估计MCID。结果方法1：平均PCS分数增加3.0单位（95％置信区间[CI] 2.2-3.9），每个单位在PHC问题中发生变化。方法2：PCS评分的平均变化增加了2.1个单位（95％CI 1.4-2.8），每个单位在PHC问题中发生变化。方法3：MCID估计为1.8个单位。结论我们对卒中患者的PCS的MCID估计为1.8至3.0单位。

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