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Evaluation of patients with multiple sclerosis and sleep disorders

机译:评估多发性硬化和睡眠障碍的患者

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Background/Aim: Sleep disorders are often reported by MS patients and various studies have shown sleep disorders to be more widespread in MS patients than in healthy control groups. However, despite the high frequency, they are often overlooked. This study aimed to determine the characteristics of fatigue and daytime sleepiness in MS patients, the underlying factors, and their relationship for testing the reliability of subjective scales and establishing when patients presenting with these symptoms should be referred to a sleep specialist. Methods: The patients enrolled in this cohort study were aged 18 years, had a confirmed diagnosis of relapsing remitting MS, were in the remission phase, had not taken steroids within the last 3 months, and had complaints of fatigue, daytime sleepiness, and sleep disorders. Patients with EDSS score 3 were admitted to the sleep laboratory for 2 days to perform 1 night of polysomnography (PSG) and a 5-nap multiple sleep latency test (MSLT) the following day. The results were evaluated with regards to the clinical scales. Results: A total of 41 patients were evaluated. Excessive daytime sleepiness was found in 14 (34.1%), and sleep quality was poor in 28 (68.29%). According to the PSG-MSLT, a sleep disorder was found in 37 patients (90.24%). A diagnosis of hypersomnolence was made in 23 (56.1%) patients, and two (4.88%) were categorized as type 2. Conclusion: It is necessary for every clinician involved in MS treatment to correctly diagnose and treat fatigue, excessive daytime sleepiness, and other sleep disorders, which increase the disability of disease. When the high prevalence of these types of disorders and the fact that they are multifactorial are taken into consideration, the timing of the referral of these patients to a sleep specialist and the implementation of objective tests become more important.
机译:背景/目的:睡眠障碍通常由MS患者报告,各种研究表明睡眠障碍在MS患者中比健康对照组更广泛。然而,尽管频率高,但它们经常被忽视。本研究旨在确定MS患者疲劳和白天嗜睡的特征,潜在的因素及其关系,以测试主观尺度的可靠性,并建立患有这些症状的患者应提及睡眠专家。方法:参加这一队列研究的患者均为年龄又令人患者& 18年来,已确诊诊断重复剩余MS,在缓解阶段,在过去3个月内没有服用类固醇,并抱怨疲劳,白天嗜睡,和睡眠障碍。 EDSS评分患者患者进入睡眠实验室2天才能在第二天进行1晚的多仪表(PSG)和5次睡眠多睡眠等待时间测试(MSLT)。对临床尺度评估结果。结果:评估41名患者。 14(34.1%)发现过度的白天嗜睡,28例睡眠质量差(68.29%)。根据PSG-MSLT,37名患者(90.24%)发现睡眠障碍。在23例(56.1%)患者中进行了过度的诊断,两次(4.88%)分类为2.结论:每个临床医生都有必要参与MS治疗,正确诊断和治疗疲劳,过度白天嗜睡,以及其他睡眠障碍,增加疾病的残疾。当这些类型的疾病的高度普及以及考虑到它们的事实时,这些患者转诊到睡眠专家的调节和客观测试的实施变得更加重要。

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