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首页> 外文期刊>Journal of surgery and medicine. >Retrospective assessment of fungal pathogens isolated from various clinical samples in a tertiary care hospital in Turkey: A cross-sectional study
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Retrospective assessment of fungal pathogens isolated from various clinical samples in a tertiary care hospital in Turkey: A cross-sectional study

机译：火鸡三级护理医院各种临床样品中分离的真菌病原体的回顾性评估：横截面研究

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Background/Aim: Fungal infections are an emerging health problem worldwide and can be caused by a broad variety of fungal pathogens. This study aimed to retrospectively determine and evaluate the fungal pathogens isolated from various clinical samples in our laboratory. Methods: A total of 996 clinical samples obtained from 803 patients who visited Karabuk University Training and Research Hospital microbiology laboratory between January 2019-December 2020 were included in this study. The BD-Phoenix 100 automated microbiology system was used for the identification of strains. Results: Among 803 patients, 52.4% were female and 47.5% were male. The median age of the patients was 76 (0-99) years. Urine (49%) and blood (27.6%) samples were evaluated the most. The most common fungal pathogen was Candida albicans (48.7%), followed by Candida tropicalis (16.5%), Candida parapsilosis (10.6%), Candida glabrata (9%), Saccharomyces cerevisiae (5.7%), and Trichosporon species (3.1%). While more than 90% of fungal strains were isolated from the inpatients, 9% were isolated from the outpatients (p0.05). Among all, 69.4% of strains were isolated from the intensive care units, followed by internal medicine (5.5%), palliative care (5%), urology (3.6%), and orthopedics and traumatology clinics (2.1%). Conclusion: Although C. albicans is still the most common fungal pathogen, the incidences of non-albicans candida and other fungi are increasing worldwide. Therefore, each country should figure out its local fungal profile and update its antifungal treatment protocols accordingly.
机译：背景/目的：真菌感染是全球的新兴健康问题，可以由广泛的真菌病原体引起。本研究旨在回顾性地确定和评估我们实验室中各种临床样本中分离的真菌病原体。方法：从803名患者获得了996例临床样本，从2019年1月到2020年1月期间访问了Karabuk大学培训和研究医院微生物学实验室。 BD-Phoenix 100自动微生物学系统用于鉴定菌株。结果：803例患者中，52.4％是女性，47.5％是男性。患者的中位年龄为76（0-99）岁。评估尿液（49％）和血液（27.6％）样品最多。最常见的真菌病原体是念珠菌（48.7％）（48.7％），其次是Candida Tropicalis（16.5％），念珠菌鹦鹉（10.6％），Candida Glabrata（9％），酿酒酵母（9％），酿酒酵母（5.7％）和Trichosporon物种（3.1％） 。虽然来自住院患者分离出超过90％的真菌菌株，但从门外剂分离9％（P <0.05）。其中69.4％的菌株与重症监护单位分离，其次是内科（5.5％），姑息治疗（5％），泌尿外科（3.6％）和骨科和创伤学诊所（2.1％）。结论：虽然C. albicans仍然是最常见的真菌病原体，但非阿尔巴文念珠菌和其他真菌的发病率在全世界正在增加。因此，每个国家都应该弄清楚其当地真菌概况并相应地更新其抗真菌治疗方案。

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