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首页> 外文期刊>Digestive Diseases and Sciences >Relationships Between Intragastric Food Maldistribution, Disturbances of Antral Contractility, and Symptoms in Functional Dyspepsia
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Relationships Between Intragastric Food Maldistribution, Disturbances of Antral Contractility, and Symptoms in Functional Dyspepsia

机译：胃内食物分布不均，胃窦收缩力障碍和功能性消化不良症状之间的关系

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摘要

We investigated the relationships between intragastric food maldistribution and antral dysmotility in functional dyspepsia, and whether these abnormalities relate to meal-induced symptoms. Intragastric distribution of food throughout gastric emptying was determined in patients (n = 24) and controls (n = 38) after a liquid nutrient meal labeled with 99mtechnetium phytate. Antral contractility was also periodically assessed by dynamic scintigraphy and postprandial symptoms were monitored with visual analog scales. Residence of food in the proximal stomach was decreased in 8 (33%) and antral contractility was increased in 9 (37.5%) and decreased in 2 (8%) patients. Proximal and distal stomach motor abnormalities were neither significantly correlated nor associated. Increased antral contractility was significantly correlated (Rs = 0.54; P < .01) with postprandial nausea. We conclude that diminished residence of food in the proximal stomach and disturbed antral contractility occur independently in different subsets of functional dyspepsia patients. Increased antral contractility seems to play a role in postprandial nausea in functional dyspepsia.
机译：我们调查了胃内食物分布不全与功能性消化不良的肛门性运动障碍之间的关系，以及这些异常是否与进餐引起的症状有关。在标有99m植酸tech的液态营养餐后，确定患者（n = 24）和对照组（n = 38）在整个胃排空中的胃内食物分布。还通过动态闪烁显像术定期评估肛门收缩性，并使用视觉模拟量表监测餐后症状。食物在胃近端的滞留率降低了8位（33％），而胃窦收缩力升高了9位（37.5％），而胃窦收缩力降低了2位（8％）。胃近端和远端胃运动异常既无显着相关也无相关性。胃窦收缩性增加与餐后恶心显着相关（Rs = 0.54； P <.01）。我们得出结论，在功能性消化不良患者的不同亚群中，食物在近端胃中的滞留量减少和窦房收缩性受损独立发生。窦房收缩力的增加似乎在功能性消化不良的餐后恶心中起作用。

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