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Bronchial Hyperresponsiveness in Irritable Bowel Syndrome

机译：肠易激综合征的支气管高反应性

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Extraintestinal symptoms are often found in patients with irritable bowel syndrome (IBS). Recent studies suggest that IBS is associated with bronchial hyperresponsiveness. But it is still arguable that the bronchial hyperresponsiveness is associated with IBS patients. The purpose of this study is to investigate the possible relationship between IBS and bronchial hyperresponsiveness. Forty-two patients with IBS and 42 control subjects were included in this study. All patients underwent pulmonary function, methacholine challenge, and skin prick tests. There was no statistical difference between the two groups with respect to percentage of all pulmonary function test parameters, including FEV1%, FCV%, FVC/FEV1, and FEF25 − 75%. Only two persons in the alternating-type IBS patient group and one person in the control group tested positive in the methacholine provocation test. But all PC20 values were above 16 mg/ml. These results do not demonstrate a relationship between bronchial hyperresponsiveness and IBS. However, a relationship might exist in a subpopulation of IBS patients.
机译：肠易激综合征（IBS）患者通常会发现肠外症状。最近的研究表明，IBS与支气管高反应性有关。但是仍然有争议的是，支气管高反应性与IBS患者有关。这项研究的目的是调查IBS和支气管高反应性之间的可能关系。本研究包括42例IBS患者和42例对照受试者。所有患者均接受了肺功能，乙酰甲胆碱激发和皮肤点刺试验。两组在所有肺功能测试参数（包括FEV1％，FCV％，FVC / FEV1 和FEF25-75 ％）的百分比方面没有统计学差异。交替型IBS患者组中只有2人，对照组中只有1人在乙酰甲胆碱激发试验中测得阳性。但所有PC20 值均高于16 mg / ml。这些结果没有证明支气管高反应性和IBS之间的关系。但是，IBS患者亚群中可能存在某种关系。

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