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Gut Reaction

机译:反应良好

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In the gleaming new Laboratories of Molecular Anthropology and Microbiome Research, opened in 2014 at the University of Oklahoma, positive air pressure keeps out external contamination, and intense ultraviolet lamps are on standby to sterilize the lab between uses. The focus of work here is not for the squeamish: Lab co-directors Christina Warinner and Cecil Lewis Jr. are digging into fossilized feces and dental plaque from long-dead humans, seeking traces of DNA from the trillions of bacteria the bodies hosted in life -just like we do today. Collectively known as the microbiome and located primarily in the large intestine, these cohabitants outnumber their host human cells at least 10 to 1. Although scientists have known of this bacterial horde for years, it's only recently that we've begun to understand its crucial role in human well-being. Some research has even suggested a link between off-kilter microbiomes and the increase in many "diseases of civilization," such as obesity, asthma and Type 2 diabetes.
机译:在俄克拉荷马大学于2014年开设的崭新的分子人类学和微生物组研究实验室中,正气压阻止外部污染,强烈的紫外线灯随时待命,以在两次使用之间对实验室进行消毒。这里的工作重点不是为了让人胆战心惊:实验室联合主任克里斯蒂娜·沃林纳和小西西·刘易斯正在挖掘长死者的化石粪便和牙菌斑,从生活在人体中的数万亿细菌中寻找DNA的痕迹。就像今天一样这些同居者通常被称为微生物组,主要位于大肠中,其宿主细胞的数量至少比宿主人细胞多10比1。尽管科学家们已经知道这种细菌群已有多年了,但直到最近我们才开始了解其细菌的重要作用。在人类福祉中。一些研究甚至表明,离群动物微生物群系与许多“文明疾病”的增加之间存在联系,例如肥胖,哮喘和2型糖尿病。

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    《Discover》 |2015年第7期|6668-69|共3页
  • 作者

    ADAM HADHAZY;

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