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J Craig Venifr on biology's next leap: digitally designed life-forms that could produce novel drugs, renewable fuels, and plentiful food for tomorrow's world

机译:J Craig Venifr谈生物学的下一个飞跃:数字化设计的生命形式,可以为明天的世界生产新颖的药物,可再生燃料和丰富的食物

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摘要

J. Craig Venter keeps riding the cusp of each new wave in biology. When researchers started analyzing genes, he launched the Institute for Genomlc Research (TIGR), decoding the genome of a bacterium for the first time in 1992. When the government announced its plan to map the human genome, he claimed he would do it first-and then he delivered results in 2001, years ahead of schedule. Armed with a deep understanding of how DNA works, Venter is now moving on to an even more extraordinary project. Starting with the stunning genetic diversity that exists in the wild, he is aiming to build custom-designed organisms that could produce clean energy, help feed the planet, and treat cancer. Venter has already transferred the genome of one species into the cell body of another. This past year he reached a major milestone, using the machinery of yeast to manufacture a genome from scratch. When he combines the steps-perhaps next year-he will have crafted a truly synthetic organism. Senior editor Pamela Weintraub discussed the implications of these efforts with Venter in DISCOVERS editorial offices.
机译:克雷格·文特尔(J. Craig Venter)始终引领着生物学的每一个新潮。当研究人员开始分析基因时,他成立了基因组研究所(TIGR),于1992年首次对细菌的基因组进行解码。当政府宣布计划绘制人类基因组图谱时,他声称他会首先这样做-然后他在2001年取得了比预期提前数年的结果。怀着对DNA的工作原理的深刻理解,Venter现在正着手进行一个更加出色的项目。从野外存在的惊人的遗传多样性开始,他的目标是建立能够产生清洁能源,帮助养活地球和治疗癌症的定制设计生物。 Venter已经将一个物种的基因组转移到另一个物种的细胞体中。去年,他达到了一个重要的里程碑,利用酵母的机械从头开始制造基因组。当他结合这些步骤时-也许明年-他将创造出一种真正的合成生物。高级编辑帕米拉·温特劳布(Pamela Weintraub)在DISCOVERS编辑部与Venter讨论了这些努力的意义。

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    《Discover》 |2010年第1期|41-42|共2页
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    PAMELA WEINTRAUB;

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