Mutant Gene Boosts Hiv Vulnerability

Josie Glausiusz

首页> 外文期刊>Discover >Mutant Gene Boosts Hiv Vulnerability

【24h】

Mutant Gene Boosts Hiv Vulnerability

机译：突变基因增强了艾滋病毒的脆弱性

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

A study of 1,200 HIV-infected U.S. Air Force servicemen has turned up a new genetic risk for HIV infection among people of African descent. A mutation already well known for conferring protection against a type of malaria appears, paradoxically, to dramatically increase the risk of HIV infection. A team of virologists, geneticists, and immunologists took a close look at the Duffy antigen receptor for chemokines, more commonly known by its acronym, DARC. The gene codes for an immune receptor on red blood cells; lack of that receptor prevents infection by Plasmodium vivax, a species of the malaria parasite.

机译：一项针对1,200名受HIV感染的美国空军军人的研究发现，非洲裔人中HIV感染的新遗传风险。自相矛盾的是，已经众所周知的赋予针对一种疟疾的保护作用的突变似乎大大增加了感染HIV的风险。一组病毒学家，遗传学家和免疫学家对Duffy趋化因子抗原受体进行了仔细研究，后者的首字母缩写是DARC。该基因编码红细胞上的免疫受体。该受体的缺乏可防止间日疟原虫（疟原虫的一种）感染。

著录项

来源
《Discover》 |2009年第1期|p.42|共1页
作者
Josie Glausiusz;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词

相似文献

外文文献
中文文献
专利

1. Societal awareness of stigma and discrimination against persons living with Human Immunodeficiency Virus (HIV) (PLHIV): Experience of clinicians, PLHIV, general population, and persons who are vulnerable to HIV [J] . Bang-on Thepthien, Supattra Srivanichakorn Journal of AIDS and HIV Research . 2016,第4期

机译：社会对感染人类免疫缺陷病毒（HIV）的人的污名和歧视的认识：临床医生，PLHIV，一般人群以及易感染HIV者的经验
2. Broad immunogenicity of a multigene, multiclade HIV-1 DNA vaccine boosted with heterologous HIV-1 recombinant modified vaccinia virus Ankara. [J] . Sandstrom E, Nilsson C, Hejdeman B, The Journal of Infectious Diseases . 2008,第10期

机译：异源HIV-1重组修饰痘苗病毒安卡拉加强了多基因，多类HIV-1 DNA疫苗的广泛免疫原性。
3. Broad Immunogenicity of a Multigene, Multiclade HIV-1 DNA Vaccine Boosted with Heterologous HIV-1 Recombinant Modified Vaccinia Virus Ankara [J] . Eric Sandström1 Charlotta Nilsson3 Bo Hejdeman1 Andreas Bråve3 Göran Bratt1 Merlin Robb4 Josephine Cox4a Thomas VanCott4a Mary Marovich4 Richard Stout6 Said Aboud7 Muhammad Bakari7 Kisali Pallangyo7 Karl Ljungberg2 Bernard Moss5 Patricia Earl5 Nelson Michael4 Deborah Birx4a Fred Mhalu7 Britta Wahren3 Gunnel Biberfeld3 and HIV Immunogenicity Study 01/02 Teamb Journal of Infectious Diseases . 2008,第10期

机译：异源HIV-1重组修饰的痘苗病毒安卡拉加强多基因，多clav HIV-1 DNA疫苗的广泛免疫原性。
4. Detection of Differentially Expressed Genes in Wild Type HIV-1 Vpr and Two HIV-1 Mutant Vprs [C] . Bandana Barman, Anirban Mukhopadhyay International Conference on Frontiers of Intelligent Computing : Theory and Applications . 2014

机译：在野生型HIV-1VPR和两个HIV-1突变VPRS中检测差异表达基因
5. Cost-Effectiveness Analysis of Nevirapine vs. Ritonavir-Boosted Lopinavir in HIV-infected Children With Peripartum Nevirapine Exposure In Resource-Constrained Areas From Payer's Perspective. [D] . Godwin, Onyeka Peter. 2014

机译：从付款人的角度来看，在资源受限地区感染了围产期尼维拉平的HIV感染儿童中，奈韦拉平vs.利托那韦促进洛匹那韦的成本-效果分析。
6. Strong HIV-Specific CD4+ and CD8+ T-Lymphocyte Proliferative Responses in Healthy Individuals Immunized with an HIV-1 DNA Vaccine and Boosted with Recombinant Modified Vaccinia Virus Ankara Expressing HIV-1 Genes [O] . Said Aboud, Charlotta Nilsson, Katarina Karlén, 2010

机译：在用HIV-1 DNA疫苗免疫并用表达HIV-1基因的重组修饰痘苗病毒安卡拉加强免疫的健康个体中强烈的HIV特异性CD4 +和CD8 + T淋巴细胞增殖反应
7. Strong HIV-Specific CD4+ and CD8+ T-Lymphocyte Proliferative Responses in Healthy Individuals Immunized with an HIV-1 DNA Vaccine and Boosted with Recombinant Modified Vaccinia Virus Ankara Expressing HIV-1 Genes▿ [O] . Aboud, Said, Nilsson, Charlotta, Karlén, Katarina, 2010

机译：在健康个体中强烈的HIV特异性CD4 +和CD8 + T淋巴细胞增殖反应，这些个体免疫了HIV-1 DNA疫苗并被表达HIV-1基因的重组修饰牛痘病毒安卡拉所增强▿

Mutant Gene Boosts Hiv Vulnerability

摘要

著录项

相似文献

相关主题

期刊订阅