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The Discoverinterview Sean Carroll

机译：采访肖恩·卡洛尔

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When Sean Carroll was a graduate student at Tufts School of Medicine in Boston, he found himself seduced by spectacular new studies of the humble fruit fly. That work, which eventually won a Nobel Prize for its principals, showed that modifying a single gene during a fly's embryonic development could transform the insect's body plan: Instead of becoming an antenna, a body extension could develop into a leg. Carroll continued to study these genes and, some years later, found that they were not restricted to fruit flies; they turned out to be part of a master tool kit that sculpts the body structures of all animals, ranging from humans to nematode worms.
机译：当肖恩·卡洛尔（Sean Carroll）在波士顿塔夫茨医学院（Tufts School of Medicine）读研究生时，他发现自己被不起眼的果蝇的惊人新研究所吸引。这项工作最终因其原理而获得了诺贝尔奖，该工作表明，在蝇的胚胎发育过程中修饰单个基因可以改变昆虫的身体计划：身体延伸可以变成一条腿，而不是成为天线。卡洛尔继续研究这些基因，并在几年后发现它们并不局限于果蝇。它们原来是雕刻所有动物身体结构的主要工具套件的一部分，从人类到线虫蠕虫。

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