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Efficiency Considerations in the Additive Hazards Model with Current Status Data

机译:具有当前状态数据的附加危害模型中的效率注意事项

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摘要

For current status data, LIN, OAKES and Ying (1998) proposed a procedure for estimation of the regression parameters in the additive hazards model that makes clever use of martingale theory. However, one of the outstanding problems posed in the paper was the issue of efficient estimation, as their estimators do not attain the semiparametric information bound. In this paper, we explore this issue and provide a characterization of the NPMLE. We conduct efficiency comparisons between the NPMLE and the procedure of LINet al. (1998) analytically and numerically through analysis of a dataset from a tumorigenicity experiment.
机译:对于当前状态数据,LIN,OAKES和Ying(1998)提出了一种利用mar理论合理估计附加危害模型中回归参数的方法。但是,本文提出的突出问题之一是有效估计的问题,因为其估计量未达到半参数信息范围。在本文中,我们探讨了这个问题并提供了NPMLE的特征。我们在NPMLE和LINet al的过程之间进行效率比较。 (1998)通过对致瘤性实验的数据集进行分析和数值分析。

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