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Museum specimens: An overlooked and valuable material for conservation genetics

机译：博物馆标本：保护遗传学的忽视和有价值的材料

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摘要

Museum specimens include genetic information from when they were collected. This historical information, which is very difficult to ascertain from samples collected currently, could be a valuable material for use in conservation genetics. However, the genetic analysis of museum specimens is technically difficult because of DNA fragmentation and the deamination of cytosine to uracil. In recent years, various methods have been developed for the genetic analysis of museum specimens, such as data analysis techniques including next-generation sequencing. The development of approaches that extract historical genetic information from museum specimens is expected to provide a new perspective on conservation genetics. This review focuses on the availability of museum specimens as genetic resources for conservation genetics. Some case studies are introduced, and perspectives on the future utility of conservation genetic studies using museum specimens are discussed. Moreover, recommended genetic analysis methods and important points for the usage of museum specimens are presented. This review provides a strong case for increasing the usage of museum specimens in conservation genetics studies in the future.
机译：博物馆标本包括从收集时的遗传信息。这一历史信息非常难以确定目前收集的样本，可能是用于保护遗传学的有价值的材料。然而，由于DNA片段化和胞嘧啶脱核，博物馆标本的遗传分析在技术上困难。近年来，已经为博物馆标本的遗传分析开发了各种方法，例如数据分析技术，包括下一代测序。预计博物馆标本从博物馆标本提取历史遗传信息的发展将提供关于保护遗传学的新视角。本综述重点介绍博物馆标本作为保护遗传学的遗传资源。介绍了一些案例研究，并讨论了使用博物馆标本的未来保护遗传研究的视角。此外，提出了推荐的遗传分析方法和博物馆标本使用的重要观点。本综述为未来保护遗传学研究中的博物馆标本的使用提供了强有力的案例。

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