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Convergence Of Body Mass With Aging: The Longitudinal Interrelationship Of Health, Weight, And Survival

机译:体重随着衰老而趋同:健康,体重和生存的纵向相互关系

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There has been ongoing debate about the health risks associated with increased body weight among the elderly population. One issue has not been investigated thoroughly is that body weight changes over time, as both the reasons and results of, the development of chronic diseases and functional disabilities. Structural models have the ability to unravel the complicated simultaneous relationship between body weight, disability, and mortality along the aging process. Using longitudinal data from the Medicare Current Beneficiary Survey from 1992 to 2001, we constructed a structural model to estimate the longitudinal dynamic relationship between weight, chronic diseases, functional status, and mortality among the aging population. A simulation of an age cohort from 65 to 100 was conducted to shew the changes in weight and health outcomes among the cohorts with different baseline weight based on the parameters estimated by the model. The elderly with normal weight at age 65 experience higher life expectancy and lower disability rates than the same age cohorts in other weight categories. The interesting prediction of our model is that the average body size of an elderly cohort will converge to the normal weight range through a process of survival, senescence, and behavioral adjustment.
机译:老年人口中与体重增加有关的健康风险一直在争论中。一个尚未被彻底研究的问题是,体重随着时间的变化而变化,这既是慢性疾病和功能障碍发展的原因和结果。结构模型具有揭示衰老过程中体重,残疾和死亡率之间复杂的同时关系的能力。利用1992年至2001年美国医疗保险当前受益人调查的纵向数据,我们构建了一个结构模型来估算体重,慢性病,功能状态和老龄人口死亡率之间的纵向动态关系。根据模型估算的参数,对65岁至100岁年龄组进行了模拟,以显示不同基线体重的人群的体重和健康结局的变化。 65岁时体重正常的老年人比其他体重类别的同龄人群的预期寿命更长,残障率更低。我们模型的有趣预测是,老年人群的平均体重将通过生存,衰老和行为调节过程收敛到正常体重范围。

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