Fifty years ago, William Russell, a classics scholar, and Rex Burch, a microbiol-ogist, outlined how the use of animals in scientific research could be made more humane. They wanted scientists to restrict the use of animals, to refine their experiments to minimise distress and to replace testing on animals with alternative techniques. Although the "3RS" have become a guiding principle, the number of animals used today remains far higher than Russell and Burch would have accepted. Finally, that may be changing. On May 5th the European Parliament voted to update the rules on the use of animals in research.
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