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Go forth and multiply

机译:继续繁殖

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摘要

After the genome, the proteome! That was the cry when the scientific big-wigs running the Human Genome Project were asked what came next. Proteomics— identifying the structure and abundance of all of the proteins in an organism, as ge-nomics sought to identify all of the genes-is a harder and more open-ended task. But, in the end, it is proteins, not genes, that do the actual work in a cell. It is therefore the failure of proteins that actually causes disease, whether that failure is the result of design faults that have been introduced by mutant genes or is just damage from wear and tear.
机译:基因组之后,蛋白质组!当问到“人类基因组计划”的科学大佬们接下来会发生什么时,这就是哭声。蛋白质组学–当基因组学试图识别所有基因时,识别生物体中所有蛋白质的结构和丰度是一项艰巨而开放的任务。但是,最后,是蛋白质而不是基因在细胞中发挥实际作用。因此,真正导致疾病的是蛋白质的失败,无论该失败是突变基因引入的设计错误的结果,还是仅仅是磨损造成的破坏。

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