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首页> 外文期刊>Infection and immunity >Immune-specific production of gamma interferon in human lymphocyte cultures in response to mumps virus.
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Immune-specific production of gamma interferon in human lymphocyte cultures in response to mumps virus.

机译:对人淋巴细胞培养物响应腮腺炎病毒的免疫特异性生产。

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The production of interferon (IFN) was investigated in human peripheral lymphocyte cultures stimulated by mumps virus. IFN-alpha and IFN-gamma were produced in lymphocyte cultures from immune donors. However, no IFN-gamma was produced in lymphocyte cultures from nonimmune donors. IFN-alpha was produced by B lymphocytes, and IFN-gamma was produced by T lymphocytes. An increase in the production of IFN-gamma resulted from the mixture of autologous macrophages in T-lymphocyte cultures. The production of IFN-gamma by T lymphocytes was found to depend on prior, possibly cellular, immunity.
机译:研究了干扰素(IFN)的人周围淋巴细胞培养物中的腮腺炎病毒刺激的培养物。 IFN-α和IFN-γ在免疫供体的淋巴细胞培养物中产生。然而,在非免疫供体的淋巴细胞培养物中没有产生IFN-Gamma。 IFN-α由B淋巴细胞产生,IFN-γ由T淋巴细胞产生。 IFN-Gamma的产生增加是由T淋巴细胞培养物中的自体巨噬细胞的混合物产生的。发现IFN-Gamma的产生淋巴细胞的产生依赖于先前,可能的细胞免疫力。

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