Sequences involved in accurate and efficient transcription of human c-myc genes microinjected into frog oocytes.

K Nishikura

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Sequences involved in accurate and efficient transcription of human c-myc genes microinjected into frog oocytes.

机译：序列参与了人c-myc基因的准确和有效转录的人c-myc基因微内注射到青蛙卵母细胞中。

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By microinjecting a series of deletion mutant constructs into Xenopus laevis oocytes, transcriptional control regions, two promoters, of the human c-myc gene were defined. In the case of the first promoter, sequences between -60 and -37 relative to the transcription start site contained an element essential for promoter activity. In the case of the second promoter, sequences between -66 and -56 relative to the initiation site appeared to be involved in accurate and efficient transcription. In both cases, the region identified as the essential promoter element contained GGGCGG or GGCGGG,GC box-like sequences, suggesting that c-myc gene promoter activity may be controlled by transcription factor Sp1 binding in the microinjected oocytes.

机译：通过将一系列缺失突变体构建体微注入到外爪蟾卵母细胞中，定义了人C-MYC基因的转录对照区域，两个启动子。在第一启动子的情况下，相对于转录起始位点的-60和-37之间的序列含有对启动子活性必需的元素。在第二启动子的情况下，相对于引发位点的-66和-56之间的序列似乎参与了准确和有效的转录。在这两种情况下，鉴定为基本启动子元素的区域含有GGGCGG或GGCGGG，GC盒状序列，表明C-MYC基因启动子活性可以通过微内注射卵母细胞中的转录因子SP1结合来控制。

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《Molecular and Cellular Biology》 |1986年第11期|共6页
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K Nishikura;
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1. Sequences involved in accurate and efficient transcription of human c-myc genes microinjected into frog oocytes. [J] . K Nishikura Molecular and Cellular Biology . 1986,第11期

机译：序列参与了人c-myc基因的准确和有效转录的人c-myc基因微内注射到青蛙卵母细胞中。
2. Sequences involved in accurate and efficient transcription of human c-myc genes microinjected into frog oocytes. [J] . K Nishikura Molecular and Cellular Biology . 1986,第11期

机译：序列参与了人c-myc基因的准确和有效转录的人c-myc基因微内注射到青蛙卵母细胞中。
3. Accurate and efficient transcription of human c-myc genes injected into Xenopus laevis oocytes. [J] . K Nishikura, S Goldflam, G A Vuocolo Molecular and Cellular Biology . 1985,第6期

机译：准确有效地转录到非洲爪蟾卵母细胞中的人类c-myc基因的转录。
4. Biophysical Studies of the Structure, Stability, and Ligand Binding Properties of G-Quadruplex DNA: Thoughts and Comparisons of the K-ras, c-MYC, and Bcl-2 Oncogene Promoter Sequence Quadruplexes [C] . Jamie M. Dettler, Edwin A. Lewis Symposium on frontiers in nucleic acids . 2011

机译：G-Quadreplex DNA的结构，稳定性和配体结合性能的生物物理研究：K-RAS，C-MYC和BCL-2癌基因促进剂序列四边形思想和比较
5. Variation in human respiratory syncytial virus transcriptional control sequences: Impact on viral gene expression and replication. [D] . Moudy, Robin M. 2005

机译：人类呼吸道合胞病毒转录控制序列的变异：对病毒基因表达和复制的影响。
6. Sequences involved in accurate and efficient transcription of human c-myc genes microinjected into frog oocytes. [O] . K Nishikura 1986

机译：微观和正确地转录人类c-myc基因转录的青蛙卵母细胞中涉及的序列。
7. Sequences involved in accurate and efficient transcription of human c-myc genes microinjected into frog oocytes. [O] . Nishikura, K 1986

机译：微观和正确地转录人类c-myc基因转录的青蛙卵母细胞中涉及的序列。
8. Stimulation of the Antigen Receptor Complex Leads to Transcriptional Activation of the c-myc Gene in Normal Human T Cells [R] . Lindsten, T., June, C. H., Thompson, C. B. 1988

机译：抗原受体复合物的刺激导致正常人T细胞中c-myc基因的转录激活

Sequences involved in accurate and efficient transcription of human c-myc genes microinjected into frog oocytes.

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