The nontranscribed chicken calmodulin pseudogene cross-hybridizes with mRNA from the slow-muscle troponin C gene.

J A Putkey; S L Carroll; A R Means

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The nontranscribed chicken calmodulin pseudogene cross-hybridizes with mRNA from the slow-muscle troponin C gene.

机译：非筛选的鸡钙调蛋白假蛋白与来自缓慢肌肉肌钙蛋白C基因的mRNA交叉杂交。

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A chicken calmodulin pseudogene with no introns was previously shown to hybridize under stringent conditions with an mRNA species present in skeletal and cardiac muscles, yet it would not hybridize to calmodulin mRNA (J. P. Stein, R. P. Munjaal, L. Lagace', E. C. Lai, B. W. O'Malley, and A. R. Means, Proc. Natl. Acad. Sci. USA 80:6485-6489, 1983). Using the pseudogene as a probe, we isolated a full-length cDNA corresponding to this mRNA from a chicken breast muscle library and showed by sequence analysis that it encodes slow-muscle troponin C and not the pseudogene product. Hybridization between the calmodulin pseudogene and slow-muscle troponin C cDNA is due to a short region of high homology in those nucleotides that encode helices B and C of troponin C and calmodulin. Genomic Southern analysis showed the calmodulin pseudogene and the gene for slow-muscle troponin C to exist as distinct single copies.

机译：没有内含子的鸡钙钙调蛋白假蛋白在严格的条件下，在骨骼和心肌中存在的mRNA物种具有杂交，但它不会杂交给钙调蛋白mRNA（JP Stein，RP Munjaal，LAGACE'，EC Lai，EC Lai，EC Lai o'Malley，Ar意味着，proc。Natl。Acad。SCI。美国80：6485-6489,1983）。使用伪基因作为探针，我们分离出与鸡胸肉肌肉图书馆对应的全长cDNA，并通过序列分析显示它编码慢肌肉肌钙蛋白C而不是假蛋白产品。钙调蛋白假基因和慢肌肉肌钙蛋白C cDNA之间的杂交是由于这些核苷酸中的高同源性的短区域，即编码肌钙蛋白C和钙调蛋白的螺旋B和C.基因组南部分析显示钙调蛋白假蛋白和缓慢肌肉肌钙蛋白C的基因作为不同的单拷贝。

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《Molecular and Cellular Biology》 |1987年第4期|共5页
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J A Putkey; S L Carroll; A R Means;
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1. The nontranscribed chicken calmodulin pseudogene cross-hybridizes with mRNA from the slow-muscle troponin C gene. [J] . J A Putkey, S L Carroll, A R Means Molecular and Cellular Biology . 1987,第4期

机译：非筛选的鸡钙调蛋白假蛋白与来自缓慢肌肉肌钙蛋白C基因的mRNA交叉杂交。
2. The nontranscribed chicken calmodulin pseudogene cross-hybridizes with mRNA from the slow-muscle troponin C gene. [J] . J A Putkey, S L Carroll, A R Means Molecular and Cellular Biology . 1987,第4期

机译：非筛选的鸡钙调蛋白假蛋白与来自缓慢肌肉肌钙蛋白C基因的mRNA交叉杂交。
3. The amino acid sequence of rabbit slow-muscle troponin I. [J] . J. Michael Wilkinson, Roger J. A. Grand The biochemical journal . 1977,第1期

机译：兔慢肌肌钙蛋白I的氨基酸序列
4. EFFECTS OF ENDOGENOUS PROTEASES EFFECTORS ON THE DEGRADATION OF TROPONIN-T AND DESMIN OF CHICKEN BRISKET MUSCLE DURING POSTMORTEM AGING1 [C] . Z.Gaile . 2007

机译：内脏蛋白酶效应对鸡RIS骨肌老化过程中肌钙蛋白-T和蛋白质降解的影响1
5. Studies of calcium and magnesium binding and exchange with mutants of troponin C and calmodulin and characterizing the interactions of calmodulin with TRP calcium channels [D] . Tikunova, Svetlana Borisovna 2000

机译：钙和镁与肌钙蛋白C和钙调蛋白突变体的结合和交换以及钙调蛋白与TRP钙通道相互作用的研究
6. The nontranscribed chicken calmodulin pseudogene cross-hybridizes with mRNA from the slow-muscle troponin C gene. [O] . J A Putkey, S L Carroll, A R Means 1987

机译：未转录的鸡钙调蛋白假基因与慢肌肌钙蛋白C基因的mRNA交叉杂交。
7. The nontranscribed chicken calmodulin pseudogene cross-hybridizes with mRNA from the slow-muscle troponin C gene. [O] . Putkey, J A, Carroll, S L, Means, A R 1987

机译：未转录的鸡钙调蛋白假基因与慢肌肌钙蛋白C基因的mRNA交叉杂交。
8. Neutron and x-ray scattering studies of the interactions between Ca2+-binding proteins and their regulatory targets: Comparisons of troponin C and calmodulin. [R] . Trewhella, J., Olah, G. A. 1993

机译：中子和X射线散射研究Ca2 +结合蛋白与其调节靶标之间的相互作用：肌钙蛋白C和钙调蛋白的比较。

The nontranscribed chicken calmodulin pseudogene cross-hybridizes with mRNA from the slow-muscle troponin C gene.

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