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Freeze-drying modeling of vial using BEM

机译：使用BEM对小瓶进行冷冻干燥建模

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摘要

The paper reports on development of Boundary Element Method (BEM) based numerical algorithm for the numerical simulation of the freeze drying process in a vial. In the paper the problems of freeze-drying modeling are covered in detail. The BEM based algorithm is developed for the axisymmetrical geometry case using the Subdoraain BEM approach. A special feature of the algorithm is an implicit representation of the interface conditions at the sublimation front, which is a great advantage of the proposed numerical scheme. As a test case the freeze drying of skim milk in a vial is selected. The numerical results show a good agreement with reference data proving that the developed numerical model is appropriate, accurate and fast in simulating the primary and secondary drying stage. The numerical analysis also shows that the time step during the secondary drying stage can be increased by a factor 100, which reduces the computational time drastically.
机译：本文报道了基于边界元方法（BEM）的数值算法的发展，该数值算法用于小瓶中冷冻干燥过程的数值模拟。在本文中，详细讨论了冷冻干燥建模的问题。使用Subdoraain BEM方法为轴对称几何情况开发了基于BEM的算法。该算法的一个特殊功能是在升华前沿隐式表示界面条件，这是所提出数值方案的一大优势。作为测试案例，选择将小瓶中的脱脂牛奶冷冻干燥。数值结果与参考数据吻合良好，证明所开发的数值模型在模拟一次和二次干燥阶段是适当，准确和快速的。数值分析还表明，二级干燥阶段的时间步长可以增加100倍，从而大大减少了计算时间。

著录项

  • 来源
    《Engineering analysis with boundary elements》 |2017年第4期|145-156|共12页
  • 作者

    M. Ramsak; J. Ravnik; M. Zadravec; M. Hribersek; J. Iljaz;

  • 作者单位

    Faculty of Mechanical Engineering, University of Maribor, Smetanova 17, SI-2000 Maribor, Slovenia;

    Faculty of Mechanical Engineering, University of Maribor, Smetanova 17, SI-2000 Maribor, Slovenia;

    Faculty of Mechanical Engineering, University of Maribor, Smetanova 17, SI-2000 Maribor, Slovenia;

    Faculty of Mechanical Engineering, University of Maribor, Smetanova 17, SI-2000 Maribor, Slovenia;

    Faculty of Mechanical Engineering, University of Maribor, Smetanova 17, SI-2000 Maribor, Slovenia;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Freeze-drying; Vial; Heat and mass transfer; Subdomain boundary element method; Sublimation;

    机译：冷冻干燥;小瓶;传热传质;子域边界元法;升华;

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