...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Environment international >Endocrine and metabolic changes in Anguilla anguilla L. following exposure to β-naphthoflavone—a microsomal enzyme inducer
【24h】

Endocrine and metabolic changes in Anguilla anguilla L. following exposure to β-naphthoflavone—a microsomal enzyme inducer

机译：暴露于β-萘黄酮（一种微粒体酶诱导剂）后，安圭拉鳗的内分泌和代谢变化

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Anguilla anguilla L. were exposed during 24 and 48 h to 2.7 μM β-naphthoflavone (BNF), a known microsomal enzyme inducer. The BNF effects on thyroid-stimulating hormone (TSH), free triiodothyronine (T3), free thyroxine (T4) and cortisol plasma levels were investigated. Alterations on plasma glucose and lactate levels were also measured as an indication of energy-mobilizing hormones alterations. BNF showed to be able to decrease significantly A. anguilla plasma T4 levels, whereas TSH, T3 and cortisol plasma remained constant. However, plasma glucose levels were significantly increased, demonstrating that intermediary metabolism has been affected. These results demonstrate that BNF a PAH-like compound alters the normal functioning of the hypothalamo-pituitary-thyroid (HPT) axis in A. anguilla.
机译：安圭拉（Anguilla anguilla L.）在24和48小时内暴露于2.7μMβ-萘黄酮（BNF）（一种已知的微粒体酶诱导剂）中。研究了BNF对甲状腺刺激激素（TSH），游离三碘甲状腺素（T3），游离甲状腺素（T4）和皮质醇血浆水平的影响。还测量了血浆葡萄糖和乳酸水平的改变，作为能量调动激素改变的指示。 BNF显示能够显着降低安圭拉血浆T4水平，而TSH，T3和皮质醇血浆保持恒定。但是，血浆葡萄糖水平显着增加，表明中间代谢受到影响。这些结果表明，BNF是一种PAH样化合物，可改变安圭。下丘脑-垂体-甲状腺（HPT）轴的正常功能。

著录项

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号