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首页> 外文期刊>Environment international >Exposure to metal mixtures and human health impacts in a contaminated area in Nanning, China
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Exposure to metal mixtures and human health impacts in a contaminated area in Nanning, China

机译：中国南宁市受污染区域的金属混合物暴露及对人类健康的影响

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Cadmium and lead have been identified as very toxic metals, which are widely present in the environment due to natural and anthropogenic emissions. Many studies have shown that the food chain is the main pathway of cadmium and lead transfer from the environment to humans. It is well documented that many factors will affect their transfer through food chains. Previous investigations on heavy metals were mostly concentrated on one contaminant in isolation. However, in real environments, exposure to mixtures of metals is ubiquitous such that cadmium pollution is invariably being associated with lead and zinc, etc. This study focuses on the contamination and health effects of the metal mixtures. For this purpose, a dietary survey was taken for 3 groups in Nanning in October 2002. Samples of soils, plants (vegetables), urine and blood of humans were measured for Cd, Fe, Cu, Zn, Ca and Pb, in addition, the urinary indicators of renal dysfunction Albumin (ALB), N-acetyl-beta-D-glucosaminidase (NAG), Beta-2-microglobulin ((β_2-MG) and Retinol-binding protein (RBP) in urine were also measured. Results showed that soil contamination with metal mixtures had caused significant renal dysfunction of the local residents living in the contaminated area, and the dose-response curve was somewhat altered by the mixed contamination of Cd and Pb as well as the intake of other minerals. The importance of mixtures of metal contamination and human health are also discussed in this paper.
机译：镉和铅已被确认为剧毒金属，由于自然和人为排放，其广泛存在于环境中。许多研究表明，食物链是镉和铅从环境向人类转移的主要途径。有据可查的是，许多因素都会影响它们通过食物链的转移。先前对重金属的研究大多集中在一种污染物上。但是，在实际环境中，金属混合物的暴露无处不在，因此镉污染总是与铅和锌等相关。这项研究的重点是金属混合物的污染和健康影响。为此，2002年10月在南宁市进行了3个小组的饮食调查。此外，还测量了人类的土壤，植物（蔬菜），尿液和血液样本中的Cd，Fe，Cu，Zn，Ca和Pb。还测量了尿中肾功能不全白蛋白（ALB），N-乙酰基-β-D-氨基葡萄糖苷酶（NAG），β-2-微球蛋白（（β_2-MG）和视黄醇结合蛋白（RBP）的泌尿指标。结果表明，金属混合物对土壤的污染已导致居住在受污染地区的当地居民严重肾功能不全，Cd和Pb的混合污染以及其他矿物质的摄入也改变了剂量-反应曲线。本文还讨论了金属污染与人类健康的混合物。

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