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首页> 外文期刊>Environment international >Long-term indoor air conditioner filtration and cardiovascular health: A randomized crossover intervention study
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Long-term indoor air conditioner filtration and cardiovascular health: A randomized crossover intervention study

机译：长期室内空调过滤和心血管健康：一项随机交叉干预研究

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摘要

The association of short-term air pollution filtration with cardiovascular health has been documented. However, the effect of long-term indoor air conditioner filtration on the association between air pollution and cardiovascular health is still unclear. We recruited 200 homemakers from Taipei and randomly assigned 100 of them to air filtration or control intervention; six home visits were conducted per year from 2013 to 2014. The participants under air filtration intervention during 2013 were reassigned to control intervention in 2014. The air pollution measurements consisted of particulate matter less than or equal to 2.5 mu m in diameter (PM2.5) and total volatile organic compounds (VOCs); blood pressure was monitored for each participant during each visit. The following morning, blood samples were collected after air pollution monitoring. The blood samples were used to analyze biological markers, including high sensitivity-C-reactive protein (hs-CRP), 8-hydroxy-2'-deoxyguanosine (8-OHdG) and fibrinogen. Household information, including cleaning, cooking, and air conditioning, was collected by a questionnaire. effects models were used to investigate the associations among air pollution measurements, blood pressure and biological markers. The results showed that increased levels of PM2.5 and total VOCs were associated with increased hs-CRP, 8-OHdG and blood pressure. The health variables were higher among participants in the control intervention phase than among those in the air filtration intervention phase. We concluded that air pollution exposure was associated with systemic inflammation, oxidative stress and elevated blood pressure. The long-term filtration of air pollution with an air conditioner filter was associated with cardiovascular health of adults.
机译：短期空气污染过滤与心血管健康之间的关联已有文献记载。但是，长期室内空调过滤对空​​气污染与心血管健康之间关系的影响仍不清楚。我们从台北市招募了200名家庭主妇，并随机分配了100名家庭主妇进行空气过滤或控制干预。从2013年到2014年，每年进行6次家访。在2013年进行空气过滤干预的参与者在2014年被重新分配为控制干预。空气污染测量包括直径小于或等于2.5微米的颗粒物（PM2.5 ）和总挥发性有机化合物（VOC）；在每次访问期间对每个参与者的血压进行监测。第二天早上，在监测空气污染后收集血液样本。血样用于分析生物学标记，包括高灵敏度C反应蛋白（hs-CRP），8-羟基-2'-脱氧鸟苷（8-OHdG）和纤维蛋白原。通过问卷调查收集了包括清洁，烹饪和空调在内的家庭信息。效应模型用于研究空气污染测量，血压和生物标志物之间的关联。结果表明，PM2.5和总VOC含量升高与hs-CRP，8-OHdG和血压升高有关。在控制干预阶段参与者的健康变量高于在空气过滤干预阶段参与者的健康变量。我们得出的结论是，空气污染暴露与全身炎症，氧化应激和血压升高有关。使用空调滤清器长期过滤空气污染与成年人的心血管健康有关。

著录项

  • 来源
    《Environment international》 |2017年第9期|91-96|共6页
  • 作者

    Chuang Hsiao-Chi; Ho Kin-Fai; Lin Lian-Yu; Chang Ta-Yuan; Hong Gui-Bing; Ma Chi-Ming; Liu I-Jung; Chuang Kai-Jen;

  • 作者单位

    Taipei Med Univ, Coll Med, Sch Resp Therapy, Taipei, Taiwan|Taipei Med Univ, Shuang Ho Hosp, Dept Internal Med, Div Pulm Med, New Taipei, Taiwan|Taipei Med Univ, Coll Med, Sch Med, Dept Internal Med, Taipei, Taiwan;

    Chinese Univ Hong Kong, Jockey Club Sch Publ Hlth & Primary Care, Hong Kong, Hong Kong, Peoples R China|Chinese Acad Sci, Inst Earth Environm, SKLLQG, Key Lab Aerosol Chem & Phys, Xian 710075, Peoples R China|Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen Municipal Key Lab Hlth Risk Anal, Shenzhen, Peoples R China;

    Natl Taiwan Univ Hosp, Dept Internal Med, Div Cardiol, Taipei, Taiwan;

    China Med Univ, Coll Publ Hlth, Dept Occupat Safety & Hlth, Taichung, Taiwan;

    Natl Taipei Univ Technol, Dept Chem Engn & Biotechnol, Taipei, Taiwan;

    St Marys Jr Coll Med Nursing & Management, Dept Cosmet Applicat & Management, Sanxing Township, Yilan County, Taiwan;

    Cardinal Tien Coll Healthcare & Management, Dept Nursing, New Taipei, Taiwan;

    Taipei Med Univ, Coll Med, Sch Med, Dept Publ Hlth, Taipei, Taiwan;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Air pollution; Indoor air filtration; Inflammation; Blood pressure; Epidemiology;

    机译：空气污染;室内空气过滤;炎症;血压;流行病学;

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