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首页> 外文期刊>Environmental Monitoring and Assessment >Genotoxic effects of the herbicide Roundup~® in the fish Cory dor as paleatus (Jenyns 1842) after short-term, environmentally low concentration exposure
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Genotoxic effects of the herbicide Roundup~® in the fish Cory dor as paleatus (Jenyns 1842) after short-term, environmentally low concentration exposure

机译：短期，环境中低浓度暴露后，除草剂Roundup〜®在鱼类科里多鱼中的遗传毒性（帕金森氏菌（Jenyns 1842））

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摘要

The glyphosate-based herbicide, Roundup~®, is one of the most used pesticides worldwide. In concert with the advent of transgenic crops resistant to glyphosate, the use of this pesticide has led to an increase in agricultural yields. The objective of this study was to evaluate the genotoxic effect that the herbicide Roundup~® (at a concentration of 6.67 μg/L, corresponding to 3.20 μg/L glyphosate) can have on the fish Corydoras paleatus. Treatment groups were exposed for 3, 6, and 9 days, and effects were analyzed using the piscine micronucleus test (PMT) and comet assay. A group subjected to filtered water only was used as a negative control. The PMT did not show differences between the control and exposed groups for any of the treatment times. In contrast, the comet assay showed a high rate of DNA damage in group exposed to Roundup for all treatment times, both for blood and hepatic cells. We conclude that for the low concentration used in this research, the herbicide shows potential genotoxic effects. Future research will be important in evaluating the effects of this substance, whose presence in the environment is ever-increasing.
机译：基于草甘膦的除草剂Roundup®是全球使用最广泛的农药之一。随着抗草甘膦转基因作物的出现，这种农药的使用导致农业产量的增加。这项研究的目的是评估除草剂Roundup®（浓度为6.67μg/ L，相当于3.20μg/ L草甘膦）对鱼类Corydoras paleatus的遗传毒性作用。治疗组分别暴露3天，6天和9天，并使用鱼微核试验（PMT）和彗星试验分析效果。仅接受过滤水的组用作阴性对照。在任何治疗时间内，PMT在对照组和暴露组之间均未显示出差异。相反，在血液和肝细胞的所有治疗时间内，暴露于Roundup的组中，彗星试验均显示出较高的DNA损伤率。我们得出结论，对于本研究中使用的低浓度，除草剂显示出潜在的遗传毒性作用。未来的研究对于评估这种物质的影响非常重要，这种物质在环境中的存在与日俱增。

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