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首页> 外文期刊>Environmental Pollution >Association between risk of birth defects occurring level and arsenic concentrations in soils of Lvliang, Shanxi province of China
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Association between risk of birth defects occurring level and arsenic concentrations in soils of Lvliang, Shanxi province of China

机译：吕梁地区出生缺陷发生风险与砷含量的关系

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摘要

The risk of birth defects is generally accredited with genetic factors, environmental causes, but the contribution of environmental factors to birth defects is still inconclusive. With the hypothesis of associations of geochemical features distribution and birth defects risk, we collected birth records and measured the chemical components in soil samples from a high prevalence area of birth defects in Shanxi province, China. The relative risk levels among villages were estimated with conditional spatial autoregressive model and the relationships between the risk levels of the villages and the 15 types of chemical elements concentration in the cropland and woodland soils were explored. The results revealed that the arsenic levels in cropland soil showed a significant association with birth defects occurring risk in this area, which is consistent with existing evidences of arsenic as a teratogen and warrants further investigation on arsenic exposure routine to birth defect occurring risk.
机译：一般而言，遗传缺陷，环境原因可以证明先天缺陷的风险，但是环境因素对先天缺陷的贡献仍然不确定。利用地球化学特征分布与出生缺陷风险之间关联的假说，我们收集了出生记录，并测量了中国山西省出生缺陷高发区的土壤样品中的化学成分。利用条件空间自回归模型估算村庄之间的相对风险水平，探索村庄的风险水平与农田和林地土壤中15种化学元素浓度之间的关系。结果表明，农田土壤中的砷水平与该地区发生先天缺陷的风险显着相关，这与砷作为致畸剂的现有证据一致，因此有必要进一步研究砷对先天缺陷发生风险的常规暴露。

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  • 来源
    《Environmental Pollution》 |2014年第8期|1-7|共7页
  • 作者

    Jilei Wu; Chaosheng Zhang; Lijun Pei; Gong Chen; Xiaoying Zheng;

  • 作者单位

    Institute of Population Research, Peking University, Beijing, China;

    GIS Centre, Ryan Institute and School of Geography and Archaeology, National University of Ireland, Golway, Ireland;

    Institute of Population Research, Peking University, Beijing, China;

    Institute of Population Research, Peking University, Beijing, China;

    Institute of Population Research, Peking University, Beijing, China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Birth defects; Chemical elements; Risk difference; Soil; Arsenic;

    机译：出生缺陷;化学元素;风险差异;泥;砷;

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