...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Environmental research >A time series analysis of the relationship between apparent temperature, air pollutants and ischemic stroke in Madrid, Spain
【24h】

A time series analysis of the relationship between apparent temperature, air pollutants and ischemic stroke in Madrid, Spain

机译：西班牙马德里表观温度，空气污染物与缺血性卒中之间关系的时间序列分析

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The understanding of the role of environment on the pathogenesis of stroke is gaining importance in the context of climate change. This study analyzes the temporal pattern of ischemic stroke (IS) in Madrid, Spain, during a 13-year period (2001-2013), and the relationship between ischemic stroke (admissions and deaths) incidence and environmental factors on a daily scale by using a quasi-Poisson regression model. To assess potential delayed and non-linear effects of air pollutants and Apparent Temperature (AT), a biometeorological index which represents human thermal comfort on IS, a lag non-linear model was fitted in a generalized additive model.The mortality rate followed a downward trend over the studied period, however admission rates progressively increased. Our results show that both increases and decreases in AT had a marked relationship with IS deaths, while hospital admissions were only associated with low AT. When analyzing the cumulative effects (for lag 0-14 days), with an AT of 1.7 degrees C (percentile 5%) a RR of 1.20 (95% CI, 1.05-1.37) for IS mortality and a RR of 1.09 (95% CI, 0.91-1.29) for morbidity is estimated. Concerning gender differences, men show higher risks of mortality in low temperatures and women in high temperatures. No significant relationship was found between air pollutant concentrations and IS morbi-mortality, but this result must be interpreted with caution, since there are strong spatial fluctuations of the former between nearby geographical areas that make it difficult to perform correlation analyses.
机译：在气候变化的背景下，对环境在中风发病机理中作用的认识日益重要。这项研究分析了西班牙马德里在13年期间（2001-2013）的缺血性卒中（IS）的时间模式，并通过使用拟泊松回归模型。为了评估空气污染物和表观温度（AT）（代表人类对IS的热舒适性）的生物气象指标的潜在延迟和非线性影响，将滞后非线性模型拟合为广义加性模型。在研究期间呈上升趋势，但是入学率逐渐提高。我们的结果表明，AT的增加和减少均与IS死亡显着相关，而住院率仅与低AT有关。在分析累积影响（滞后0-14天）时，AT为1.7摄氏度（百分数5％），IS死亡率为1.20（95％CI，1.05-1.37），RR为1.09（95％） CI（0.91-1.29）估计发病率。关于性别差异，男人在低温下显示出更高的死亡率，而在高温下则显示出更高的死亡率。在空气污染物浓度和IS发病率之间未发现显着关系，但是必须谨慎解释这一结果，因为前者在附近地理区域之间存在很大的空间波动，因此很难进行相关分析。

著录项

  • 来源
    《Environmental research》 |2019年第6期|349-358|共10页
  • 作者

    Roye Dominic; Zarrabeitia Maria T.; Riancho Javier; Santurtun Ana;

  • 作者单位

    Univ Santiago de Compostela, Dept Geog, Santiago De Compostela, Spain|Univ Porto, Dept Geog, Porto, Portugal|CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain;

    Univ Cantabria, Dept Physiol & Pharmacol, Unit Legal Med, Santander, Spain;

    Hosp Sierrallana, Inst Invest Sanitaria IDIVAL, Ctr Invest Biomed Red Enfermedades CIBERNED, Dept Neurol, Santander, Spain;

    Univ Cantabria, Dept Physiol & Pharmacol, Unit Legal Med, Santander, Spain;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Ischemic stroke; Air pollutants; Apparent temperature; Mortality; Admissions;

    机译：缺血性中风;空气污染物;表观温度;死亡率;入院;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号