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首页> 外文期刊>Environmental research >Household air pollution from biomass-burning cookstoves and metabolic syndrome, blood lipid concentrations, and waist circumference in Honduran women: A cross-sectional study
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Household air pollution from biomass-burning cookstoves and metabolic syndrome, blood lipid concentrations, and waist circumference in Honduran women: A cross-sectional study

机译:洪都拉斯妇女因燃烧生物质炊具和代谢综合征,血脂浓度和腰围而造成的家庭空气污染:一项横断面研究

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摘要

Background: Household air pollution from cooking with solid fuels affects nearly 3 billion people worldwide and is responsible for an estimated 2.5 million premature deaths and 77 million disability-adjusted life years annually. Investigating the effect of household air pollution on indicators of cardiometabolic disease, such as metabolic syndrome, can help clarify the pathways between this widespread exposure and cardiovascular diseases, which are increasing in low- and middle-income countries.Methods: Our cross-sectional study of 150 women in rural Honduras (76 with traditional stoves and 74 with cleaner-burning Justa stoves) explored the effect of household air pollution exposure on cardiovascular disease risk factors. Household air pollution was measured by stove type and 24-h average kitchen and personal fine particulate matter [PM2.5] mass and black carbon concentrations. Health endpoints included non-fasting total cholesterol, high-density lipoprotein, calculated low-density lipoprotein, triglycerides, waist circumference to indicate abdominal obesity, and presence of metabolic syndrome (defined by current modified international guidelines: waist circumference = 80 cm plus any two of the following: triglycerides 200 mg/dL, HDL 50 mg/dL, systolic blood pressure = 130 mmHg, diastolic blood pressure = 85 mmHg, or glycated hemoglobin 5.6%).Results: Forty percent of women met the criteria for metabolic syndrome. The prevalence ratio [PR] for metabolic syndrome (versus normal) per interquartile range increase in kitchen PM2.5 and kitchen black carbon was 1.16 (95% confidence interval [CI]: 1.01-1.34) per 312 mu g/m(3) increase in PM2.5, and 1.07 (95% CI: 1.03-1.12) per 73 mu g/m(3) increase in black carbon. There is suggestive evidence of a stronger effect in women = 40 years of age compared to women 40 (p-value for interaction = 0.12 for personal PM2.5). There was no evidence of associations between all other exposure metrics and health endpoints.Conclusions: The prevalence of metabolic syndrome among our study population was high compared to global estimates. We observed a suggestive effect between metabolic syndrome and exposure to household air pollution. These results for metabolic syndrome may be driven by specific syndrome components, such as blood pressure. Longitudinal research with repeated health and exposure measures is needed to better understand the link between household air pollution and indicators of cardiometabolic disease risk.
机译:背景:固体燃料烹饪产生的家庭空气污染影响了全球近30亿人,每年估计造成250万人过早死亡和7700万残疾调整生命年。研究家庭空气污染对代谢综合征等心脏代谢疾病指标的影响,可以帮助弄清这种广泛暴露与心血管疾病之间的途径,在低收入和中等收入国家中这种疾病正在增加。方法:我们的横断面研究洪都拉斯农村地区的150名妇女(76名使用传统炉灶,74名使用更清洁的Justa炉灶)探讨了家庭空气污染暴露对心血管疾病危险因素的影响。通过炉灶类型和24小时平均厨房以及个人细颗粒物[PM2.5]的质量和黑碳浓度来衡量家庭空气污染。健康终点包括非禁食的总胆固醇,高密度脂蛋白,计算出的低密度脂蛋白,甘油三酸酯,表明腹部肥胖的腰围以及代谢综合征的存在(由现行国际标准定义:腰围> = 80 cm加上任何以下两个中的两个:甘油三酸酯> 200 mg / dL,HDL <50 mg / dL,收缩压> = 130 mmHg,舒张压> = 85 mmHg,或糖化血红蛋白> 5.6%)结果:40%的女性代谢综合征的标准。厨房PM2.5和厨房黑碳每四分位间距增加的代谢综合症(相对于正常)的患病率[PR]为每312μg / m 1.16(95%置信区间[CI]:1.01-1.34)(3) PM2.5的增加和黑炭每增加73μg / m(3)会增加1.07(95%CI:1.03-1.12)。有迹象表明,年龄大于等于40岁的女性比年龄小于40岁的女性有更强的作用(互动的p值=个人PM2.5 = 0.12)。没有证据表明所有其他暴露指标与健康终点之间存在关联。结论:与全球估算值相比,我们研究人群中代谢综合征的患病率较高。我们观察到代谢综合征和暴露于家庭空气污染之间的暗示影响。代谢综合征的这些结果可能受特定的综合征成分(例如血压)驱动。为了更好地了解家庭空气污染与心脏代谢疾病风险指标之间的联系,需要对健康和接触措施进行纵向研究。

著录项

  • 来源
    《Environmental research》 |2019年第3期|46-55|共10页
  • 作者单位

    Colorado State Univ, Dept Environm & Radiol Hlth Sci, Ft Collins, CO 80523 USA;

    Colorado State Univ, Dept Environm & Radiol Hlth Sci, Ft Collins, CO 80523 USA;

    Colorado State Univ, Dept Environm & Radiol Hlth Sci, Ft Collins, CO 80523 USA;

    Colorado State Univ, Dept Environm & Radiol Hlth Sci, Ft Collins, CO 80523 USA|Gettysburg Coll, Hlth Sci Program, Gettysburg, PA 17325 USA;

    Colorado State Univ, Dept Environm & Radiol Hlth Sci, Ft Collins, CO 80523 USA;

    Univ Michigan, Sch Med, Div Cardiovasc Med, Ann Arbor, MI USA;

    Colorado State Univ, Dept Hlth & Exercise Sci, Ft Collins, CO 80523 USA;

    Colorado State Univ, Dept Environm & Radiol Hlth Sci, Ft Collins, CO 80523 USA|Colorado State Univ, Dept Mech Engn, Ft Collins, CO 80523 USA;

    Colorado State Univ, Dept Environm & Radiol Hlth Sci, Ft Collins, CO 80523 USA;

    Colorado State Univ, Dept Mech Engn, Ft Collins, CO 80523 USA;

    Colorado State Univ, Dept Environm & Radiol Hlth Sci, Ft Collins, CO 80523 USA;

    Johns Hopkins Univ, Dept Environm Hlth Sci, Bloomberg Sch Publ Hlth, Baltimore, MD 21205 USA;

    Trees Water & People, Ft Collins, CO USA;

    Trees Water & People, Ft Collins, CO USA|Asociac Hondurena Desarrollo, Tegucigalpa, Honduras;

    Colorado State Univ, Dept Environm & Radiol Hlth Sci, Ft Collins, CO 80523 USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Indoor air pollution; Cookstoves; Cardiovascular disease; Global health; Latin America;

    机译:室内空气污染;炉灶;心血管疾病;全球健康;拉丁美洲;

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