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首页> 外文期刊>Environmental research >Health effects of living near an incinerator: A systematic review of epidemiological studies, with focus on last generation plants
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Health effects of living near an incinerator: A systematic review of epidemiological studies, with focus on last generation plants

机译：焚化炉附近生活的健康效果：对流行病学研究的系统综述，重点是持续的植物

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摘要

Huge reductions in incinerators' emissions occurred over time, and results of older studies cannot be directly generalized to modem plants. We conducted a systematic review of the epidemiologic evidence of the health effects of incinerators, classifying plants in three generations, according to emission limits. A systematic search identified 63 epidemiologic studies, published in English, investigating health effects of incinerators on humans. We focused on cancer, cardio-cerebrovascular diseases (CVD) and respiratory diseases, pregnancy outcomes and congenital anomalies. Only six studies in the general population were on third generation incinerators providing data on pregnancy outcomes and congenital anomalies. Given the heterogeneity of methods, the abundance of ecological/semi-ecological studies and the lack of reliable quantitative measures of exposure in several studies we did not perform any meta-analysis. No excesses emerged concerning all cancers and lung cancer. An excess of non-Hodgkin lymphoma was reported in some earlier studies, but not for second generation plants. Possible excesses of soft tissue sarcomas were confined to earlier incinerators and the areas closer to the plants. No clear association emerged for CVD and diseases of the respiratory system. Several different pregnancy outcomes were considered, and no consistent association emerged, in spite of a few positive results. Studies were negative for congenital anomalies as a whole. Sporadic excesses were reported in a few studies for specific types of anomalies, but no consistent pattern emerged. Evaluation of the evidence was hindered by heterogeneity in reporting and classification of outcomes across studies. Direct evidence from third generation plants is scarce. Methodological issues in study design (mainly related to exposure assessment, confounding and ecological design) and analysis make interpretation of results complex. In spite of this, the overall evidence suggests that, if there were any excesses at all for older incinerators, they were modest at most. Additional monitoring of third generation plants needs to overcome methodological weaknesses.
机译：随着时间的推移发生焚烧炉排放的巨大减少，较旧研究的结果不能直接推广到调制解调器工厂。根据排放限制，我们对焚化炉的健康效果的流行病学证据进行了系统的审查，这是分类的三代人。系统搜索确定了63项流行病学研究，以英语发表，调查了焚化炉对人类的健康影响。我们专注于癌症，心血管血管疾病（CVD）和呼吸系统疾病，妊娠结算和先天性异常。一般人群中只有六项研究是第三代焚烧炉，提供有关妊娠结局和先天性异常的数据。鉴于方法的异质性，丰富的生态/半生态学研究以及若干研究中的暴露缺乏可靠的定量措施我们没有进行任何荟萃分析。没有过度出现在所有癌症和肺癌上。在一些早期的研究中报道了过量的非霍奇金淋巴瘤，但不是第二代植物。可能的软组织肉瘤可能局限于早期的焚化炉，并且靠近植物的区域。对于呼吸系统的CVD和疾病没有明确的关联。考虑到几种不同的怀孕结果，并且尽管有一些积极的结果，但没有出现一致的关联。研究是一个整体先天性异常的研究。在一些关于特定类型的异常的研究中报告了零星过量，但没有出现一致的模式。对证据的评估受到在研究中的报告和分类中的异质性。来自第三代植物的直接证据是稀缺的。研究设计中的方法论（主要与曝光评估，混淆和生态设计相关）和分析对结果复杂的解释。尽管如此，总体证据表明，如果老年焚烧员一切都有过多，它们最多是谦虚的。第三代植物的额外监测需要克服方法论弱点。

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  • 来源
    《Environmental research》 |2020年第5期|109305.1-109305.18|共18页
  • 作者

    Eva Negri; Francesca Bravi; Simona Catalani; Valentina Guercio; Francesca Metruccio; Angelo Moretto; Carlo La Vecchia; Pietro Apostoli;

  • 作者单位

    Dipartimento di Scienze Biomediche e Cliniche Universita degli Studi di Milano Milan Italy;

    Dipartimento di Scienze Cliniche e di Comunita Universita degli Studi di Milano Milan Italy;

    Dipartimento Specialita Medico-Chirurgiche Scienze Radiologiche e Sanita Pubblica Universita degli Studi di Brescia Brescia Italy;

    Dipartimento di Scienze Biomediche e Cliniche Universita degli Studi di Milano Milan Italy;

    ICPS International Centre for Pesticides and Health Risk Prevention ASST Fatebenefratelli Sacco Milan Italy;

    Dipartimento di Scienze Biomediche e Cliniche Universita degli Studi di Milano Milan Italy ICPS International Centre for Pesticides and Health Risk Prevention ASST Fatebenefratelli Sacco Milan Italy;

    Dipartimento di Scienze Cliniche e di Comunita Universita degli Studi di Milano Milan Italy;

    Dipartimento Specialita Medico-Chirurgiche Scienze Radiologiche e Sanita Pubblica Universita degli Studi di Brescia Brescia Italy;

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  • 正文语种 eng
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  • 关键词

    Waste incineration; Cancer; Cardiovascular diseases; Diseases of the respiratory system; Reproduction;

    机译：垃圾焚烧;癌症;心血管疾病;呼吸系统的疾病;繁殖;

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