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Long-term residential road traffic noise and mortality in a Danish cohort

机译：丹麦队列的长期住宅道路交通噪音和死亡率

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摘要

Transportation noise is a growing public health concern worldwide and epidemiological evidence has linked road traffic noise with mortality. However, incongruent effect estimates have been reported between incidence and mortality studies. Therefore, the present study aimed to investigate whether long-term exposure to residential road traffic noise at the most and least exposed facades was associated with all-cause, cardiovascular disease (CVD), ischemic heart disease (IHD), stroke, respiratory, or cancer mortality in a Danish cohort study. In a cohort of 52,758 individuals from Copenhagen and Aarhus, we estimated road traffic noise at the most and least exposed facades, as well as ambient air pollution, at all present and historical residential addresses from 1987 to 2016. Using the Danish cause of death register we identified cause-specific mortality. Analyses were conducted using Cox proportional hazards models. Ten-year time-weighted mean road traffic noise exposure at the most exposed facade was associated with an 8% higher risk for all-cause mortality per interquartile range (IQR; 10.4 dB) higher exposure level (95% CI: 1.05-1.11). Higher risks were also observed for CVD (HR = 1.13, 95% CI: 1.06-1.19) and stroke (HR = 1.11, 95% CI: 0.99-1.25) mortality. Road traffic noise at the least exposed facade (per IQR; 8.4 dB) was associated with CVD (HR = 1.09, 95% CI: 1.03-1.15), IHD (HR = 1.10, 95% CI: 1.01-1.21) and stroke (HR = 1.06, 95% CI: 0.95-1.19) mortality. Results were robust to adjustment for PM_(2.5) and NO_2. In conclusion, this study adds to the body of evidence linking exposure to road traffic noise with higher risk of mortality.
机译：运输噪音是全球范围内越来越多的公共卫生问题，流行病学证据与死亡率有关的道路交通噪音。然而，在发病​​率和死亡率研究之间存在不一致的效果估计。因此，本研究旨在调查最多和最少暴露的外墙的长期暴露是否与全源，心血管疾病（CVD），缺血性心脏病（IHD），中风，呼吸或或丹麦队列研究中的癌症死亡率。在来自哥本哈根和奥胡斯的52,758个个体的群组中，我们在1987年至2016年的所有目前和历史住宅地址中估计了最多和最少暴露的外墙以及环境空气污染的道路交通噪音。使用丹麦死亡登记册我们确定了特异性原因死亡率。使用Cox比例危险模型进行分析。在最曝光的外观上的十年时间加权平均公路交通噪声暴露与每条胎面范围（IQR; 10.4 dB）更高的暴露水平的所有原因死亡率的风险高8％（95％CI：1.05-1.11） 。对于CVD（HR = 1.13,95％CI：1.06-1.19）和中风（HR = 1.11,95％CI：0.99-1.25）死亡率也观察到较高的风险。最小暴露的外立面（每个IQR; 8.4 dB）的道路交通噪声与CVD（HR = 1.09,95％CI：1.03-1.15），IHD（HR = 1.10,95％CI：1.01-1.21）和中风（ HR = 1.06,95％CI：0.95-1.19）死亡率。结果对PM_（2.5）和NO_2进行调整稳健。总之，本研究增加了对道路交通噪声接触的证据组成，具有更高的死亡风险。

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  • 来源
    《Environmental research》 |2020年第8期|109633.1-109633.8|共8页
  • 作者

    Jesse D. Thacher; Ulla A. Hvidtfeldt; Aslak H. Poulsen; Ole Raaschou-Nielsen; Matthias Ketzel; Jorgen Brandt; Steen S. Jensen; Kim Overvad; Anne Tjonneland; Thomas Muenzel; Mette Sorensen;

  • 作者单位

    Diet Genes and Environment Danish Cancer Society Research Center Copenhagen Denmark;

    Diet Genes and Environment Danish Cancer Society Research Center Copenhagen Denmark;

    Diet Genes and Environment Danish Cancer Society Research Center Copenhagen Denmark;

    Diet Genes and Environment Danish Cancer Society Research Center Copenhagen Denmark Department of Environmental Science Aarhus University Roskilde Denmark;

    Department of Environmental Science Aarhus University Roskilde Denmark Global Centre for Clean Air Research (GCARE) University of Surrey Guildford United Kingdom;

    Department of Environmental Science Aarhus University Roskilde Denmark;

    Department of Environmental Science Aarhus University Roskilde Denmark;

    Department of Cardiology Aalborg University Hospital Aalborg Denmark Department of Public Health Aarhus University Aarhus C Denmark;

    Diet Genes and Environment Danish Cancer Society Research Center Copenhagen Denmark Department of Public Health University of Copenhagen Denmark;

    University Medical Center Mainz of the Johannes Gutenberg University Center for Cardiology Cardiology I Mainz Germany;

    Diet Genes and Environment Danish Cancer Society Research Center Copenhagen Denmark Department of Natural Science and Environment Roskilde University Roskilde Denmark;

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  • 正文语种 eng
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  • 关键词

    Road traffic noise; Mortality; Cardiovascular disease; Cause specific; Epidemiology; Cohort;

    机译：道路交通噪音;死亡;心血管疾病;原因具体;流行病学;队列;

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