Abstract Isolation and characterization of a respirable particle fraction from residential house-dust
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Isolation and characterization of a respirable particle fraction from residential house-dust

机译：住宅粉尘中可吸入颗粒物的分离与表征

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摘要

AbstractIndoor air pollution has caused increasing concern in recent years. As we spend most of our lives indoors, it is crucial to understand the health effects caused by indoor air pollution. Household dust serve as good proxy for accessing indoor air pollution, especially smaller dust particles that can pass into the lungs are of interest. In this study we present an efficient method for the isolation of dust particles in the respirable size range. The respirable fraction was recovered from vacuum cleaner bags, separated by stepwise sieving, followed by characterization for size, morphology, surface area, organic content and elemental composition. The respirable fraction was obtained in a yield of 0.6% with a specific surface area of 2.5m2/g and a Mass Median Aerodynamic Diameter of 3.73 ± 0.15µm. Aluminum and zink were the dominating metals measured in the dust, whereas the major mineral components were found to be silicon dioxide and calcium carbonate. The fraction of organic matter in the dust was measured to be 69 ± 1%. The organic matrix contained bacterial and fungi and a presence of skin fragments. We present here an efficient and fast method for the isolation of dust particles in the respirable size range. That is of considerable value due to the need for large quantities of respirable particle fractions to conduct toxicological studies and risk assessment work.Highlights•House dust is an important environmental matrix to monitor.•A method for the isolation of dust particles in the respirable size range was developed.•The study presents a comprehensive characterization of house dust in the respirable size range.•This method may be a valuable for risk assessment following an inhalation exposure to house dust.
机译： 摘要 室内空气污染近年来引起了越来越多的关注。由于我们大部分时间都在室内度过，因此了解室内空气污染对健康的影响至关重要。家用粉尘可作为获得室内空气污染的良好替代品，尤其令人关注的是可以进入肺部的较小粉尘颗粒。在这项研究中，我们提出了一种有效方法，用于隔离可吸入尺寸范围内的灰尘颗粒。从真空吸尘器袋中回收可吸入部分，通过逐步筛分分离，然后表征尺寸，形态，表面积，有机物含量和元素组成。获得可呼吸部分，产率为0.6％，比表面积为2.5m 2 / g，质量平均空气动力学直径为3.73±0.15µm。铝和锌是粉尘中的主要金属，而主要的矿物成分是二氧化硅和碳酸钙。灰尘中有机物的含量经测量为69±1％。有机基质含有细菌和真菌以及皮肤碎片。我们在这里提出了一种有效且快速的方法，用于隔离可吸入尺寸范围内的灰尘颗粒。由于需要大量可吸入颗粒物进行毒理学研究和风险评估工作，因此具有相当大的价值。 突出显示 • 房屋灰尘是要监控的重要环境矩阵。 < ce：label>• 开发了一种可呼吸尺寸范围内的灰尘颗粒分离方法。 • 该研究提出了一项全面的建议特征 • 在吸入室内灰尘后，该方法可能对风险评估很有价值。

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  • 来源
    《Environmental research》 |2018年第2期|284-290|共7页
  • 作者

    Åsa Gustafsson; Annette M. Krais; András Gorzsás; Thomas Lundh; Per Gerde;

  • 作者单位

    Swetox, Karolinska Institutet, Unit of Toxicology Sciences,Department of Chemistry, Umeå University;

    Swetox, Karolinska Institutet, Unit of Toxicology Sciences,Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University;

    Department of Chemistry, Umeå University;

    Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University;

    Swetox, Karolinska Institutet, Unit of Toxicology Sciences,Institute of Environmental Medicine (IMM), Karolinska Institutet;

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  • 正文语种 eng
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  • 关键词

    Indoor air; House dust; Respirable; Inhalation; Health; Particle characterization;

    机译：室内空气;室内灰尘;可呼吸;吸入;健康;颗粒表征;

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