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首页> 外文期刊>Environmental research >Cigarettes vs. e-cigarettes: Passive exposure at home measured by means of airborne marker and biomarkers
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Cigarettes vs. e-cigarettes: Passive exposure at home measured by means of airborne marker and biomarkers

机译:香烟与电子香烟:在家中通过空气传播标记物和生物标记物测量的被动暴露量

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摘要

Background: There is scarce evidence about passive exposure to the vapour released or exhaled from electronic cigarettes (e-cigarettes) under real conditions. The aim of this study is to characterise passive exposure to nicotine from e-cigarettes' vapour and conventional cigarettes' smoke at home among non-smokers under real-use conditions. Methods: We conducted an observational study with 54 non-smoker volunteers from different homes: 25 living at home with conventional smokers, 5 living with nicotine e-cigarette users, and 24 from control homes (not using conventional cigarettes neither e-cigarettes). We measured airborne nicotine at home and biomarkers (cotinine in saliva and urine). We calculated geometric mean (GM) and geometric standard deviations (GSD). We also performed ANOVA and Student's t tests for the log-transformed data. We used Bonferroni-corrected t-tests to control the family error rate for multiple comparisons at 5%. Results: The GMs of airborne nicotine were 0.74 μg/m~3 (GSD=4.05) in the smokers' homes, 0.13 μg/m~3 (GSD=2.4) in the e-cigarettes users' homes, and 0.02 μg/m~3 (GSD=3.51) in the control homes. The GMs of salivary cotinine were 0.38 ng/ml (GSD=2.34) in the smokers' homes, 0.19 ng/ml (GSD = 2.17) in the e-cigarettes users' homes, and 0.07 ng/ml (GSD=1.79) in the control homes. Salivary cotinine concentrations of the non-smokers exposed to e-cigarette's vapour at home (all exposed ≥ 2 h/day) were statistically significant different that those found in non-smokers exposed to second-hand smoke ≥ 2 h/ day and in non-smokers from control homes. Conclusions: The airborne markers were statistically higher in conventional cigarette homes than in e-cigarettes homes (5.7 times higher). However, concentrations of both biomarkers among non-smokers exposed to conventional cigarettes and e-cigarettes' vapour were statistically similar (only 2 and 1.4 times higher, respectively). The levels of airborne nicotine and cotinine concentrations in the homes with e-cigarette users were higher than control homes (differences statistically significant). Our results show that non-smokers passively exposed to e-cigarettes absorb nicotine.
机译:背景:几乎没有证据表明在真实条件下被动暴露于电子烟(电子烟)释放或呼出的蒸气。这项研究的目的是在实际使用条件下,对非吸烟者在家中从电子烟的蒸气和常规香烟的烟中被动暴露尼古丁的特征。方法:我们对来自不同家庭的54名非吸烟志愿者进行了一项观察性研究:25名居住在常规吸烟者家中,5名居住在尼古丁电子烟使用者中,以及24名来自对照家庭(既不使用传统香烟又不使用电子烟)。我们在家中测量了空气中的尼古丁和生物标志物(唾液和尿液中的可卡因)。我们计算了几何平均值(GM)和几何标准差(GSD)。我们还对对数转换后的数据进行了ANOVA和Student t检验。我们使用Bonferroni校正的t检验将家族比较的错误率控制在5%。结果:吸烟者家中空气中尼古丁的GMs分别为0.74μg/ m〜3(GSD = 4.05),电子烟使用者家中的GMs为0.13μg/ m〜3(GSD = 2.4)和0.02μg/ m 〜3(GSD = 3.51)。吸烟者家中唾液可替宁的GMs为0.38 ng / ml(GSD = 2.34),电子烟使用者家中的唾液可替宁GMs为0.19 ng / ml(GSD = 2.17),而在吸烟者家中为0.07 ng / ml(GSD = 1.79)。控制房屋。在家中暴露于电子烟蒸气中的非吸烟者(全部暴露≥2 h /天)的唾液可替宁浓度与在二手烟中≥2 h /天暴露的非吸烟者和非吸烟者的唾液中可替宁浓度存在统计学差异。 -从控制室吸烟者。结论:常规卷烟家庭中的空气传播标记在统计学上高于电子烟家庭(高5.7倍)。但是,在暴露于常规香烟和电子烟蒸气的非吸烟者中,两种生物标志物的浓度在统计上相似(分别仅高2倍和1.4倍)。电子烟使用者家中空气中尼古丁和可替宁的浓度高于对照家(差异具有统计学意义)。我们的结果表明,被动吸烟的非吸烟者会吸收尼古丁。

著录项

  • 来源
    《Environmental research》 |2014年第11期|76-80|共5页
  • 作者单位

    Tobacco Control Unit, Cancer Prevention and Control Program, Institut Catala d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain,Catalan Network of Smoke-free Hospitals, L'Hospitalet de Llobregat, Barcelona, Spain,Cancer Prevention and Control Group, Institut d'Investigacio Biomedica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain,Addictions Unit, Institute of Neurosciences, Hospital Clinic de Barcelona - IDIBAPS, Barcelona, Spain,Department of Clinical Sciences, Universitat de Barcelona, Barcelona, Spain;

    Tobacco Control Unit, Cancer Prevention and Control Program, Institut Catala d'Oncologia, Av. Granvia de l'Hospitalet, 199-203, L'Hospitalet de Llobregat, 08908 Barcelona, Spain,Cancer Prevention and Control Group, Institut d'Investigacio Biomedica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain,Biostatistics Unit, Department of Basic Sciences, Universitat International de Catalunya, Sant Cugat del Valles, Barcelona, Spain;

    Tobacco Control Unit, Cancer Prevention and Control Program, Institut Catala d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain,Cancer Prevention and Control Group, Institut d'Investigacio Biomedica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain,Department of Clinical Sciences, Universitat de Barcelona, Barcelona, Spain;

    Tobacco Control Unit, Cancer Prevention and Control Program, Institut Catala d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain,Cancer Prevention and Control Group, Institut d'Investigacio Biomedica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain,Department of Clinical Sciences, Universitat de Barcelona, Barcelona, Spain;

    IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain;

    IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain,Department of Experimental and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain;

    Health Plan Directorate, Ministry of Health, Generalitat de Catalunya, Spain,Department of Public Health, Universitat de Barcelona, Barcelona, Spain;

    Tobacco Control Unit, Cancer Prevention and Control Program, Institut Catala d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain,Catalan Network of Smoke-free Hospitals, L'Hospitalet de Llobregat, Barcelona, Spain,Cancer Prevention and Control Group, Institut d'Investigacio Biomedica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain,Department of Clinical Sciences, Universitat de Barcelona, Barcelona, Spain;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Tobacco smoke pollution; Biological markers; Electronic cigarette; Electronic nicotine delivery system (ENDS);

    机译:烟草烟雾污染;生物标志物;电子烟;电子尼古丁输送系统(ENDS);

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