Greatly Enhanced Removal of Volatile Organic Carcinogens by a Genetically Modified Houseplant, Pothos lvy (Epipremnum aureum) Expressing the Mammalian Cytochrome P450 2e1 Gene

Zhang Long; Routsong Ryan; Strand Stuart E.

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Greatly Enhanced Removal of Volatile Organic Carcinogens by a Genetically Modified Houseplant, Pothos lvy (Epipremnum aureum) Expressing the Mammalian Cytochrome P450 2e1 Gene

机译：基因改造的室内植物，表达哺乳动物细胞色素P450 2e1基因的Pothos lvy（金黄色的Epipremnum aureum）大大增强了挥发性有机致癌物的去除

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The indoor air in urban homes of developed countries is usually contaminated with significant levels of volatile organic carcinogens (VOCs), such as formaldehyde, benzene, and chloroform. There is a need for a practical, sustainable technology for the removal of VOCs in homes. Here we show that a detoxifying transgene, mammalian cytochrome P450 2e1 can be expressed in a houseplant, Epipremnum aureum, pothos ivy, and that the resulting genetically modified plant has sufficient detoxifying activity against benzene and chloroform to suggest that biofilters using transgenic plants could remove VOCs from home air at useful rates.

机译：发达国家城市家庭的室内空气通常被大量的挥发性有机致癌物（VOC）污染，例如甲醛，苯和氯仿。需要一种实用的，可持续的技术来去除家庭中的VOC。在这里，我们显示了一种排毒转基因哺乳动物细胞色素P450 2e1可以在室内植物，金黄色葡萄球菌，pothos常春藤中表达，并且所得的转基因植物对苯和氯仿具有足够的排毒活性，表明使用转基因植物的生物滤池可以去除VOC。从家用飞机以有用的价格获得。

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来源
《Environmental Science & Technology》 |2019年第1期|325-331|共7页
作者
Zhang Long; Routsong Ryan; Strand Stuart E.;
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作者单位

Univ Washington, Dept Civil & Environm Engn, Box 355014, Seattle, WA 98195 USA;

Univ Washington, Dept Civil & Environm Engn, Box 355014, Seattle, WA 98195 USA;

Univ Washington, Dept Civil & Environm Engn, Box 355014, Seattle, WA 98195 USA;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
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1. Degradation of Low Molecular Weight Volatile Organic Compounds by Plants Genetically Modified with Mammalian Cytochrome P450 2E1 [J] . C. ANDREW JAMES, GANG XIN, SHARON L. DOTY, Environmental Science & Technology . 2008,第1期

机译：哺乳动物细胞色素P450 2E1基因修饰的植物对低分子量挥发性有机化合物的降解
2. Identification of a Mg-protoporphyrin IX monomethyl ester cyclase homologue, EaZIP, differentially expressed in variegated Epipremnum aureum 'Golden Pothos' is achieved through a unique method of comparative study using tissue regenerated plants. [J] . Hung C. Y., Sun Y. H., Chen J. J., Journal of Experimental Botany . 2010,第5期

机译：通过使用组织再生植物的独特对比研究，可以鉴定出在杂色的 Epipremnum aureum “ Golden Pothos”中差异表达的Mg-原卟啉IX单甲酯环化酶同系物EaZIP。
3. Identification of a Mg-protoporphyrin IX monomethyl ester cyclase homologue, EaZIP, differentially expressed in variegated Epipremnum aureum ‘Golden Pothos’ is achieved through a unique method of comparative study using tissue regenerated plants [J] . Chiu-Yueh Hung, Ying-Hsuan Sun, Jianjun Chen, Journal of Experimental Botany . 2010,第5期

机译：通过使用组织再生植物的独特对比研究，可以鉴定在杂色表皮金黄色葡萄球菌“金丝瓜”中差异表达的镁原卟啉IX单甲酯环化酶同系物EaZIP。
4. Differential expression profile of cytochrome p450 2E1 (CYP2E1) related genes associated with carbon tetrachloride-induced hepatotoxicity. [D] . Sreedevi, Avasarala. 2005

机译：与四氯化碳诱导的肝毒性相关的细胞色素p450 2E1（CYP2E1）相关基因的差异表达谱。
5. Identification of a Mg-protoporphyrin IX monomethyl ester cyclase homologue EaZIP differentially expressed in variegated Epipremnum aureum ‘Golden Pothos’ is achieved through a unique method of comparative study using tissue regenerated plants [O] . Chiu-Yueh Hung, Ying-Hsuan Sun, Jianjun Chen, -1

机译：通过使用组织再生植物的独特对比研究可以鉴定在杂色表生金黄色葡萄球菌金丝瓜中差异表达的镁原卟啉IX单甲酯环化酶同源物EaZIP。
6. Identification of a Mg-protoporphyrin IX monomethyl ester cyclase homologue, EaZIP, differentially expressed in variegated Epipremnum aureum ‘Golden Pothos’ is achieved through a unique method of comparative study using tissue regenerated plants [O] . Hung, Chiu-Yueh, Sun, Ying-Hsuan, Chen, Jianjun, 2010

机译：通过使用组织再生植物的独特对比研究，可以鉴定在杂色表生金黄色葡萄球菌“金丝瓜”中差异表达的镁原卟啉IX单甲酯环化酶同源物EaZIP。
7. Use of Genetic Engineering to Produce a Mutated Cytochrome P450 Enzyme Capable of Both Oxidizing and Reductively Dechlorinating Hazardous Organic Chemicals [R] . Alworth, W. L. , Mullin, D. A. 2000

机译：使用基因工程生产一种能够氧化和还原性脱氯危险有机化学品的突变细胞色素p450酶

Greatly Enhanced Removal of Volatile Organic Carcinogens by a Genetically Modified Houseplant, Pothos lvy (Epipremnum aureum) Expressing the Mammalian Cytochrome P450 2e1 Gene

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